Polyphenolic compounds (PC) are among the most abundant secondary metabolites in
nature. They are widely distributed in the world and can be found in fruits, cereals, tea …

Polydatin is a natural potent stilbenoid polyphenol and a resveratrol derivative with
improved bioavailability. Polydatin possesses potential biological activities predominantly …

Spinal cord injury (SCI), which is characterized by excessive inflammatory cell infiltration
and accumulation of oxidative substance, would severely impede neurological functional …

Neurodegenerative diseases are known for their wide range of harmful conditions related to
progressive cell damage, nervous system connections and neuronal death. These …

Usually, polyphenols help address numerous health issues caused by oxidative stress. Tea
is a popular beverage (rich in polyphenols) with abundant health promoting and disease …

Skin aging is a complex biological process influenced by a combination of intrinsic and
extrinsic factors, leading to cumulative alterations in the structure, function, and appearance …

Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …

About 4% of the world's population has type 2 diabetes mellitus (T2DM), and the available
hypoglycemic drugs for treating diabetes have some side effects. Therefore, research on the …

Background Due to the complex pathophysiological mechanisms involved in cancer
progression and metastasis, current therapeutic approaches lack efficacy and have …

Spinal cord injury (SCI), a fatal condition, is characterized by progressive tissue degradation
and extreme functional deficits with limited treatment options. Hesperetin, a natural flavonoid …