The peptide vaccine of the future

A Nelde, HG Rammensee, JS Walz - Molecular & cellular proteomics, 2021 - ASBMB
The approach of peptide-based anticancer vaccination has proven the ability to induce
cancer-specific immune responses in multiple studies for various cancer entities. However …

Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches

S Parvizpour, MM Pourseif, J Razmara, MA Rafi… - Drug Discovery …, 2020 - Elsevier
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …

Peptide‐based therapeutic cancer vaccine: current trends in clinical application

W Liu, H Tang, L Li, X Wang, Z Yu, J Li - Cell Proliferation, 2021 - Wiley Online Library
The peptide‐based therapeutic cancer vaccines have attracted enormous attention in recent
years as one of the effective treatments of tumour immunotherapy. Most of peptide‐based …

An overview of in silico vaccine design against different pathogens and cancer

K Kardani, A Bolhassani, A Namvar - Expert Review of Vaccines, 2020 - Taylor & Francis
Introduction Due to overcome the hardness of the vaccine design, computational
vaccinology is emerging widely. Prediction of T cell and B cell epitopes, antigen processing …

Cancer/testis antigens: from serology to mRNA cancer vaccine

C Fan, H Qu, X Wang, N Sobhani, L Wang, S Liu… - Seminars in cancer …, 2021 - Elsevier
Cancer/testis antigens (CTAs) are a group of tumor antigens expressed in numerous cancer
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …

A domain-based vaccine construct against SARS-CoV-2, the causative agent of COVID-19 pandemic: development of self-amplifying mRNA and peptide vaccines

MM Pourseif, S Parvizpour, B Jafari, J Dehghani… - BioImpacts …, 2020 - pmc.ncbi.nlm.nih.gov
Introduction: Coronavirus disease 2019 (COVID-19) is undoubtedly the most challenging
pandemic in the current century with more than 293,241 deaths worldwide since its …

Cancer biomarkers: Emerging trends and clinical implications for personalized treatment

A Passaro, M Al Bakir, EG Hamilton, M Diehn, F André… - Cell, 2024 - cell.com
The integration of cancer biomarkers into oncology has revolutionized cancer treatment,
yielding remarkable advancements in cancer therapeutics and the prognosis of cancer …

[HTML][HTML] Genome-level therapeutic targets identification and chimeric Vaccine designing against the Blastomyces dermatitidis

S Mursaleen, A Sarfraz, M Shehroz, A Zaman… - Heliyon, 2024 - cell.com
Blastomyces dermatitidis is a thermally dimorphic fungus that can cause serious and
sometimes fatal infections, including blastomycosis. After spore inhalation, a pulmonary …

Cancer testis antigen subfamilies: Attractive targets for therapeutic vaccine

S Ren, Z Zhang, M Li, D Wang… - International …, 2023 - spandidos-publications.com
Cancer‑testis antigen (CTA) is a well‑accepted optimal target library for cancer diagnosis
and treatment. Most CTAs are located on the X chromosome and aggregate into large gene …

Echinococcus granulosus as a promising therapeutic agent against triplenegative breast cancer

S Sadr, H Borji - Current Cancer Therapy Reviews, 2023 - ingentaconnect.com
Breast cancer is a major cause of cancer deaths in women, with approximately 1.2 million
new cases per year. Current treatment options for breast cancer include surgery, radiation …