De novo clustering of long-read transcriptome data using a greedy, quality value-based algorithm

K Sahlin, P Medvedev - Journal of Computational Biology, 2020 - liebertpub.com
Long-read sequencing of transcripts with Pacific Biosciences (PacBio) Iso-Seq and Oxford
Nanopore Technologies has proven to be central to the study of complex isoform …

Accurate binning of metagenomic contigs using composition, coverage, and assembly graphs

V Mallawaarachchi, Y Lin - Journal of Computational Biology, 2022 - liebertpub.com
Metagenomics enables the recovery of various genetic materials from different species, thus
providing valuable insights into microbial communities. Metagenomic binning group …

MetaCoAG: binning metagenomic contigs via composition, coverage and assembly graphs

V Mallawaarachchi, Y Lin - International Conference on Research in …, 2022 - Springer
Metagenomics has allowed us to obtain various genetic material from different species and
gain valuable insights into microbial communities. Binning plays an important role in the …

[KNJIGA][B] Genome-scale algorithm design: bioinformatics in the era of high-throughput sequencing

V Mäkinen, D Belazzougui, F Cunial, AI Tomescu - 2023 - books.google.com
Presenting the fundamental algorithms and data structures that power bioinformatics
workflows, this book covers a range of topics from the foundations of sequence analysis …

Improving metagenomic binning results with overlapped bins using assembly graphs

VG Mallawaarachchi, AS Wickramarachchi… - Algorithms for Molecular …, 2021 - Springer
Background Metagenomic sequencing allows us to study the structure, diversity and ecology
in microbial communities without the necessity of obtaining pure cultures. In many …

De Novo Clustering of Long-Read Transcriptome Data Using a Greedy, Quality-Value Based Algorithm

K Sahlin, P Medvedev - … in Computational Molecular Biology: 23rd Annual …, 2019 - Springer
Long-read sequencing of transcripts with PacBio Iso-Seq and Oxford Nanopore
Technologies has proven to be central to the study of complex isoform landscapes in many …

GraphBin2: Refined and overlapped binning of metagenomic contigs using assembly graphs

VG Mallawaarachchi… - … on Algorithms in …, 2020 - researchnow.flinders.edu.au
Metagenomic sequencing allows us to study structure, diversity and ecology in microbial
communities without the necessity of obtaining pure cultures. In many metagenomics …

SpaRC: scalable sequence clustering using Apache Spark

L Shi, X Meng, E Tseng, M Mascagni, Z Wang - Bioinformatics, 2019 - academic.oup.com
Motivation Whole genome shotgun based next-generation transcriptomics and
metagenomics studies often generate 100–1000 GB sequence data derived from tens of …

A framework for space-efficient variable-order Markov models

F Cunial, J Alanko, D Belazzougui - Bioinformatics, 2019 - academic.oup.com
Motivation Markov models with contexts of variable length are widely used in bioinformatics
for representing sets of sequences with similar biological properties. When models contain …

[KNJIGA][B] Leveraging big data and machine learning technologies for accurate and scalable genomic analysis

L Shi - 2020 - search.proquest.com
The revolution in next-generation DNA sequencing technologies is leading to explosive data
growth in genomics, posing a significant challenge to the computing infrastructure and …