Dps is a universally conserved dual-action DNA-binding and ferritin protein

K Orban, SE Finkel - Journal of Bacteriology, 2022 - Am Soc Microbiol
The DNA-binding protein from starved cells, Dps, is a universally conserved prokaryotic
ferritin that, in many species, also binds DNA. Dps homologs have been identified in the vast …

Biomolecular condensates as stress sensors and modulators of bacterial signaling

M Sasazawa, DT Tomares, WS Childers… - PLoS …, 2024 - journals.plos.org
Microbes exhibit remarkable adaptability to environmental fluctuations. Signaling
mechanisms, such as two-component systems and secondary messengers, have long been …

Global DNA compaction in stationary-phase bacteria does not affect transcription

R Janissen, MMA Arens, NN Vtyurina, Z Rivai… - Cell, 2018 - cell.com
In stationary-phase Escherichia coli, Dps (DNA-binding protein from starved cells) is the
most abundant protein component of the nucleoid. Dps compacts DNA into a dense complex …

More than just a phase: the search for membraneless organelles in the bacterial cytoplasm

EA Abbondanzieri, AS Meyer - Current genetics, 2019 - Springer
The bacterial cytoplasm, once thought to be a relatively undifferentiated reaction medium,
has now been recognized to have extensive microstructure. This microstructure includes …

[HTML][HTML] Geometric approach to nonequilibrium hasty shortcuts

SS Chittari, Z Lu - The Journal of Chemical Physics, 2023 - pubs.aip.org
Complex and even non-monotonic responses to external control can be found in many
thermodynamic systems. In such systems, nonequilibrium shortcuts can rapidly drive the …

Deep learning on the 2-dimensional Ising model to extract the crossover region with a variational autoencoder

N Walker, KM Tam, M Jarrell - Scientific reports, 2020 - nature.com
The 2-dimensional Ising model on a square lattice is investigated with a variational
autoencoder in the non-vanishing field case for the purpose of extracting the crossover …

The Affective Ising Model: A computational account of human affect dynamics

T Loossens, M Mestdagh, E Dejonckheere… - PLoS Computational …, 2020 - journals.plos.org
The human affect system is responsible for producing the positive and negative feelings that
color and guide our lives. At the same time, when disrupted, its workings lie at the basis of …

Bridging DNA contacts allow Dps from E. coli to condense DNA

S Shahu, N Vtyurina, M Das, AS Meyer… - Nucleic Acids …, 2024 - academic.oup.com
The DNA-binding protein from starved cells (Dps) plays a crucial role in maintaining
bacterial cell viability during periods of stress. Dps is a nucleoid-associated protein that …

An introduction to magnetic tweezers

D Dulin - Single Molecule Analysis: Methods and Protocols, 2023 - Springer
Magnetic tweezers are a single-molecule force and torque spectroscopy technique that
enable the mechanical interrogation in vitro of biomolecules, such as nucleic acids and …

Investigating fundamental principles of nonequilibrium assembly using temperature-sensitive copolymers

SS Chittari, AC Obermeyer… - Journal of the American …, 2023 - ACS Publications
Both natural biomaterials and synthetic materials benefit from complex energy landscapes
that provide the foundation for structure–function relationships and environmental sensitivity …