Erratic cell proliferation is the initial symptom of cancer, which can eventually metastasize to
other organs. Before cancer becomes metastatic, its spread is triggered by pro-angiogenic …

Pyridine-based ring structures are widely employed in drug design due to their significant
impact on pharmacological activity, resulting in the development of various broad-spectrum …

A novel set of thiazolylhydrazonothiazoles bearing an indole moiety were synthesized by
subjection reactions of carbothioamide derivative and hydrazonoyl chlorides (or α …

One crucial strategy for the treatment of breast cancer involves focusing on the Vascular
Endothelial Growth Factor Receptor (VEGFR-2) signaling system. Consequently, the …

Terephthalohydrazide chitosan hydrogel (TCs) was prepared and investigated as an
ecofriendly biopolymeric catalyst for synthesis of some novel thiazole and thiadiazole …

The catalytic activity of chitosan (Cs) and grafted Cs led to the preparation of
terephthalohydrazide Cs Schiff's base hydrogel (TCsSB), which was then investigated as an …

Lung cancer is one of the most common cancer types of cancer with the highest mortality
rates. However, while epidermal growth factor receptor (EGFR) is an important parameter for …

In this study, a novel series of pyridine-based thiadiazole derivatives (NTD1-NTD5) were
synthesized as prospective anti-inflammatory agents by combining substituted carboxylic …

A new series of N-aryl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine,(8a-x) have been
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …

Breast cancer remains a major global health issue, particularly affecting women and
contributing significantly to mortality rates. Current treatments for estrogen receptor‐positive …