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[HTML][HTML] Marine arthropods as a source of antimicrobial peptides
Peptide therapeutics play a key role in the development of new medical treatments. The
traditional focus on endogenous peptides has shifted from first discovering other natural …
traditional focus on endogenous peptides has shifted from first discovering other natural …
Investigating the binding mechanism of sphingosine kinase 1/2 inhibitors: Insights into subtype selectivity by homology modeling, molecular dynamics simulation and …
J Zhang, M Zhang, J Yu, Y Shang, K Jiang, Y Jia… - Journal of Molecular …, 2020 - Elsevier
Abstract Sphingosine 1-phosphate (S1P) is a lipid signaling molecule that is implicated in a
variety of pathologies, including cancer, inflammation and pulmonary arterial hypertension …
variety of pathologies, including cancer, inflammation and pulmonary arterial hypertension …
Targeting sphingosine kinase 1 for the treatment of pulmonary arterial hypertension
K Yang, K Jiang, Z Xu, Y Song… - Future Medicinal Chemistry, 2019 - Taylor & Francis
Pulmonary arterial hypertension (PAH), characterized by high morbidity and mortality, is a
serious hazard to human life. Until now, the long-term survival of the PAH patients is still …
serious hazard to human life. Until now, the long-term survival of the PAH patients is still …