Animal cells use a wide variety of mechanisms to slow or prevent replication of viruses.
These mechanisms are usually mediated by antiviral proteins whose expression and …

Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that
localize in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into …

Interferons (IFNs) are important cytokines that regulate immune responses through the
activation of hundreds of genes, including interferon-induced transmembrane proteins …

Targeting tumor-infiltrating regulatory T cells (Tregs) is an efficient way to evoke an anti-
tumor immune response. However, how Tregs maintain their fragility and stability remains …

SARS-CoV-2 can cause lung diseases, such as pneumonia and acute respiratory distress
syndrome, and multi-system dysfunction. Post-translational modifications (PTMs) related to …

Lysine methylation is a common posttranslational modification (PTM) of histones that is
important for the epigenetic regulation of transcription and chromatin in eukaryotes …

Interferon-inducible transmembrane protein 3 (IFITM3) is essential for innate defense
against influenza virus in mice and humans. IFITM3 localizes to endolysosomes where it …

Interferon-induced transmembrane protein 3 (IFITM3) is a cellular endosome-and lysosome-
localized protein that restricts numerous virus infections. IFITM3 is activated by …

Interferons (IFNs) are antiviral cytokines that defend against viral infections by inducing the
expression of interferon-stimulated genes (ISGs). Interferon-inducible transmembrane …

The interferon‐induced transmembrane (IFITM) proteins protect host cells from diverse virus
infections. IFITM proteins also incorporate into HIV‐1 virions and inhibit virus fusion and cell …