Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Peptide-functionalized,-assembled and-loaded nanoparticles in cancer therapy

J Dai, M Ashrafizadeh, AR Aref, G Sethi, YN Ertas - Drug Discovery Today, 2024 - Elsevier
The combination of peptides and nanoparticles in cancer therapy has shown synergistic
results. Nanoparticle functionalization with peptides can increase their targeting ability …

Multifunctional tumor-targeting Carbon dots for Tumor Microenvironment activated ferroptosis and immunotherapy in Cancer Treatment

Y Bao, G Li, S Li, H Zhang, X Wu, R Yan… - … applied materials & …, 2023 - ACS Publications
As an emerging cancer treatment strategy, ferroptosis is distinguished by the perturbation of
lipid metabolism equilibrium and the accumulation of lipid peroxidation. However, the …

Bio-orthogonal click chemistry strategy for PD-L1-targeted imaging and pyroptosis-mediated chemo-immunotherapy of triple-negative breast cancer

Y Wang, Y Chen, DK Ji, Y Huang, W Huang… - Journal of …, 2024 - Springer
Background The combination of programmed cell death ligand-1 (PD-L1) immune
checkpoint blockade (ICB) and immunogenic cell death (ICD)-inducing chemotherapy has …

Designing peptide-based nanoinhibitors of programmed cell death ligand 1 (PD-L1) for enhanced chemo-immunotherapy

F **e, S Tang, Y Zhang, Y Zhao, Y Lin, Y Yao… - ACS …, 2024 - ACS Publications
The combination of immune checkpoint blockade (ICB) and chemotherapy has shown
significant potential in the clinical treatment of various cancers. However, circulating …

Chitosan-functionalized nanobubbles for precision oncology: advances in targeted cancer therapeutics

V Pandey, T Pandey - Journal of Materials Chemistry B, 2024 - pubs.rsc.org
The convergence of nanotechnology and cancer therapeutics has opened new frontiers in
the development of advanced drug delivery systems. Among the various nanocarriers …

Chitosan nanoparticles for targeted cancer therapy: A review of stimuli-responsive, passive, and active targeting strategies

JRMH Al-Shadidi, S Al-Shammari… - International Journal …, 2024 - Taylor & Francis
Despite all major advancements in drug discovery and development in the pharmaceutical
industry, cancer is still one of the most arduous challenges for the scientific community. The …

[HTML][HTML] Advances in the delivery of anticancer drugs by nanoparticles and chitosan-based nanoparticles

J Prieložná, V Mikušová, P Mikuš - International Journal of Pharmaceutics …, 2024 - Elsevier
Cancer is the leading cause of death globally, and conventional treatments have limited
efficacy with severe side effects. The use of nanotechnology has the potential to reduce the …

Techniques and applications in 3D bioprinting with chitosan bio-inks for drug delivery: A review

Z Yao, X Feng, Z Wang, Y Zhan, X Wu, W **e… - International Journal of …, 2024 - Elsevier
Three-dimensional bioprinting leverages computer-aided design to construct tissues and
organs with specialized bioinks. A notable biomaterial for this purpose is chitosan, a natural …

Design of PD‐L1‐Targeted Lipid Nanoparticles to Turn on PTEN for Efficient Cancer Therapy

Y Kim, J Choi, EH Kim, W Park, H Jang… - Advanced …, 2024 - Wiley Online Library
Lipid nanoparticles (LNPs) exhibit remarkable mRNA delivery efficiency, yet their majority
accumulate in the liver or spleen after injection. Tissue‐specific mRNA delivery can be …