The impact of infections and inflammation during pregnancy on the develo** fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

Epidemiological studies have shown a clear association between maternal infection and
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …

Accumulating evidence suggests that gut microbiota plays a role in the pathogenesis of
schizophrenia via the microbiota–gut–brain axis. This study sought to investigate whether …

Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …

Epidemiologic studies, including prospective birth cohort investigations, have implicated
maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

The develo** brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Schizophrenia is a heterogeneous psychiatric disorder that is poorly treated with current
therapies. In this brief review, we provide an update regarding the use of animal models to …

A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …

Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …