The fast-growing field of photo-driven theranostics based on aggregation-induced emission

Z Zhang, M Kang, H Tan, N Song, M Li, P **ao… - Chemical Society …, 2022 - pubs.rsc.org
Photo-driven theranostics, also known as phototheranostics, relying on the diverse excited-
state energy conversions of theranostic agents upon photoexcitation represents a significant …

Mitochondria-targeted smart AIEgens: Imaging and therapeutics

H Li, H Kim, C Zhang, S Zeng, Q Chen, L Jia… - Coordination Chemistry …, 2022 - Elsevier
Mitochondria are not only the main energy source of the cell but are also involved in the
regulation of important physiology and processes of diseases including cancers. Therefore …

An AIE photosensitizer with simultaneous type I and type II ROS generation: efficient bacterial elimination and hypoxic tumor ablation

Y Wang, J Liao, Y Lyu, Q Guo, Z Zhu… - Advanced Functional …, 2023 - Wiley Online Library
Aggregation induced emission (AIE) photosensitizers have attracted great attention due to
their good performance in photodynamic therapy (PDT). However, the therapeutic effect of …

Cascade reactions by nitric oxide and hydrogen radical for anti-hypoxia photodynamic therapy using an activatable photosensitizer

J Sun, X Cai, C Wang, K Du, W Chen… - Journal of the …, 2021 - ACS Publications
Organelle-targeted activatable photosensitizers are attractive to improve the specificity and
controllability of photodynamic therapy (PDT), however, they suffer from a big problem in the …

Near‐infrared thermally activated delayed fluorescence nanoparticle: a metal‐free photosensitizer for two‐photon‐activated photodynamic therapy at the cell and …

F Fang, Y Yuan, Y Wan, J Li, Y Song, WC Chen… - Small, 2022 - Wiley Online Library
Thermally activated delayed fluorescence (TADF) materials with extremely small singlet‐
triplet energy offsets have opened new horizons for the development of metal‐free …

Molecular engineering of AIE-active boron clustoluminogens for enhanced boron neutron capture therapy

W Ma, Y Wang, Y Xue, M Wang, C Lu, W Guo… - Chemical …, 2024 - pubs.rsc.org
The development of boron delivery agents bearing an imaging capability is crucial for boron
neutron capture therapy (BNCT), yet it has been rarely explored. Here we present a new …

Recent advances of smart AIEgens for photoacoustic imaging and phototherapy

Y Shi, D Zhu, D Wang, B Liu, X Du, G Wei… - Coordination Chemistry …, 2022 - Elsevier
The design of novel nanomaterials and nanoprobes used to diagnose and treat
innumerable diseases has exhibited great potential in biomedical fields, which further …

Aggregation-induced fluorogens in bio-detection, tumor imaging, and therapy: a review

YL Balachandran, X Jiang - Ccs Chemistry, 2022 - chinesechemsoc.org
Aggregation-induced emission (AIE) fluorogens produce strong, stable fluorescence upon
aggregation, thus enabling a new frontier in bio-detection, cell imaging, and other …

Ferroptosis: challenges and opportunities for nanomaterials in cancer therapy

Q Liu, Y Zhao, H Zhou, C Chen - Regenerative Biomaterials, 2023 - academic.oup.com
Ferroptosis, a completely new form of regulated cell death, is mainly caused by an
imbalance between oxidative damage and reductive protection and has shown great anti …

Aggregation-induced generation of reactive oxygen species: mechanism and photosensitizer construction

J Ni, Y Wang, H Zhang, JZ Sun, BZ Tang - Molecules, 2021 - mdpi.com
Luminogens with aggregation-induced emission (AIEgens) have been widely applied in the
field of photodynamic therapy. Among them, aggregation-induced emission photosensitizers …