Arterial stiffness, a leading marker of risk in hypertension, can be measured at material or
structural levels, with the latter combining effects of the geometry and composition of the …

Alzheimer's disease (AD) is the most common neurodegenerative disorder seen in age-
dependent dementia. There is currently no effective treatment for AD, which may be …

Approximately 10% of dementia patients have idiopathic normal pressure hydrocephalus
(iNPH), an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and …

The retina is an emerging CNS target for potential noninvasive diagnosis and tracking of
Alzheimer's disease (AD). Studies have identified the pathological hallmarks of AD …

Objectives To investigate glymphatic function in Alzheimer's disease (AD) using the diffusion
tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the …

Longitudinal clinical–pathological studies have increasingly recognized the importance of
mixed pathologies (the coexistence of one or more neurodegenerative and cerebrovascular …

Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Objective In the brain, protein waste removal is partly performed by paravascular pathways
that facilitate convective exchange of water and soluble contents between cerebrospinal …

Vascular contributions to cognitive impairment and dementia (VCID) are characterized by
the aging neurovascular unit being confronted with and failing to cope with biological insults …

Aging-related cellular and molecular processes including low-grade inflammation are major
players in the pathogenesis of cardiovascular disease (CVD) and Alzheimer's disease (AD) …