TXNDC5, a newly discovered disulfide isomerase with a key role in cell physiology and pathology
E Horna-Terrón, A Pradilla-Dieste… - International journal of …, 2014 - mdpi.com
Thioredoxin domain-containing 5 (TXNDC5) is a member of the protein disulfide isomerase
family, acting as a chaperone of endoplasmic reticulum under not fully characterized …
family, acting as a chaperone of endoplasmic reticulum under not fully characterized …
The role and mechanism of TXNDC5 in diseases
X Wang, H Li, X Chang - European Journal of Medical Research, 2022 - Springer
Thioredoxin domain-containing protein 5 (TXNDC5) is a member of the protein disulfide
isomerase (PDI) family. It can promote the formation and rearrangement of disulfide bonds …
isomerase (PDI) family. It can promote the formation and rearrangement of disulfide bonds …
The human protein disulfide isomerase gene family
JJ Galligan, DR Petersen - Human genomics, 2012 - Springer
Enzyme-mediated disulfide bond formation is a highly conserved process affecting over one-
third of all eukaryotic proteins. The enzymes primarily responsible for facilitating thiol …
third of all eukaryotic proteins. The enzymes primarily responsible for facilitating thiol …
[HTML][HTML] Comprehensive association analysis of candidate genes for generalized vitiligo supports XBP1, FOXP3, and TSLP
SA Birlea, Y **, DC Bennett, DM Herbstman… - Journal of investigative …, 2011 - Elsevier
We previously carried out a genome-wide association study of generalized vitiligo (GV) in
non-Hispanic whites, identifying 13 confirmed susceptibility loci. In this study, we re …
non-Hispanic whites, identifying 13 confirmed susceptibility loci. In this study, we re …
A critical role of the thioredoxin domain containing protein 5 (TXNDC5) in redox homeostasis and cancer development
HA Chawsheen, Q Ying, H Jiang, Q Wei - Genes & diseases, 2018 - Elsevier
Correct folding of nascent peptides occurs in the endoplasmic reticulum (ER). It is a
complicate process primarily accomplished by the coordination of multiple redox proteins …
complicate process primarily accomplished by the coordination of multiple redox proteins …
[HTML][HTML] TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration, vasculogenic mimicry and angiogenesis by down-regulating SERPINF1 and …
B Xu, J Li, X Liu, C Li, X Chang - Oncotarget, 2017 - ncbi.nlm.nih.gov
TXNDC5 (thioredoxin domain-containing protein 5) catalyzes disulfide bond formation,
isomerization and reduction. Studies have reported that TXNDC5 expression is increased in …
isomerization and reduction. Studies have reported that TXNDC5 expression is increased in …
[HTML][HTML] Investigating a pathogenic role for TXNDC5 in tumors
X Chang, B Xu, L Wang, Y Wang… - … journal of oncology, 2013 - spandidos-publications.com
The expression of TXNDC5, which is induced by hypoxia, stimulates cell proliferation and
angiogenesis. The increased cell proliferation, angiogenesis and hypoxia are main features …
angiogenesis. The increased cell proliferation, angiogenesis and hypoxia are main features …
The role and mechanism of TXNDC5 in disease progression
M Jiao, Y Zhang, X Song, B Xu - Frontiers in Immunology, 2024 - frontiersin.org
Thioredoxin domain containing protein-5 (TXNDC5), also known as endothelial protein-
disulfide isomerase (Endo-PDI), is confined to the endoplasmic reticulum through the …
disulfide isomerase (Endo-PDI), is confined to the endoplasmic reticulum through the …
[PDF][PDF] Could ER stress be a major link between oxidative stress and autoimmunity in vitiligo
Could ER Stress Be A Major Link Between Oxidative Stress And Autoimmunity In Vitiligo?
Page 1 Volume 1 • Issue 3 • 1000123 Pigmentary Disorders ISSN: 2376-0427 JPD, hybrid …
Page 1 Volume 1 • Issue 3 • 1000123 Pigmentary Disorders ISSN: 2376-0427 JPD, hybrid …
TXNDC5 contributes to rheumatoid arthritis by down-regulating IGFBP1 expression
J Li, B Xu, C Wu, X Yan, L Zhang… - Clinical & Experimental …, 2018 - academic.oup.com
The thioredoxin domain-containing 5 (TXNDC5) gene is associated with susceptibility to
rheumatoid arthritis (RA) and exhibits increased expression in the synovial tissues. TXNDC5 …
rheumatoid arthritis (RA) and exhibits increased expression in the synovial tissues. TXNDC5 …