Putting the “mental” back in “mental disorders”: a perspective from research on fear and anxiety

V Taschereau-Dumouchel, M Michel, H Lau… - Molecular …, 2022‏ - nature.com
Mental health problems often involve clusters of symptoms that include subjective
(conscious) experiences as well as behavioral and/or physiological responses. Because the …

Decoding cognition from spontaneous neural activity

Y Liu, MM Nour, NW Schuck, TEJ Behrens… - Nature Reviews …, 2022‏ - nature.com
In human neuroscience, studies of cognition are rarely grounded in non-task-
evoked,'spontaneous' neural activity. Indeed, studies of spontaneous activity tend to focus …

Psilocybin desynchronizes the human brain

JS Siegel, S Subramanian, D Perry, BP Kay… - Nature, 2024‏ - nature.com
A single dose of psilocybin, a psychedelic that acutely causes distortions of space–time
perception and ego dissolution, produces rapid and persistent therapeutic effects in human …

Automated optimization of TMS coil placement for personalized functional network engagement

CJ Lynch, IG Elbau, TH Ng, D Wolk, S Zhu, A Ayaz… - Neuron, 2022‏ - cell.com
Transcranial magnetic stimulation (TMS) is used to treat multiple psychiatric and
neurological conditions by manipulating activity in particular brain networks and circuits, but …

Functional connectivity map** for rTMS target selection in depression

IG Elbau, CJ Lynch, J Downar… - American Journal of …, 2023‏ - Am Psychiatric Assoc
Objective: Repetitive transcranial magnetic stimulation (rTMS) protocols increasingly use
subgenual anterior cingulate cortex (sgACC) functional connectivity to individualize …

Default-mode network streams for coupling to language and control systems

EM Gordon, TO Laumann, S Marek… - Proceedings of the …, 2020‏ - National Acad Sciences
The human brain is organized into large-scale networks identifiable using resting-state
functional connectivity (RSFC). These functional networks correspond with broad cognitive …

Temporally and anatomically specific contributions of the human amygdala to threat and safety learning

Z Wen, CM Raio, EF Pace-Schott… - Proceedings of the …, 2022‏ - National Acad Sciences
Neural plasticity in subareas of the rodent amygdala is widely known to be essential for
Pavlovian threat conditioning and safety learning. However, less consistent results have …

Functional connectomics in depression: insights into therapies

Y Chai, YI Sheline, DJ Oathes, NL Balderston… - Trends in Cognitive …, 2023‏ - cell.com
Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has …

Human amygdala compared to orbitofrontal cortex connectivity, and emotion

ET Rolls, G Deco, CC Huang, J Feng - Progress in Neurobiology, 2023‏ - Elsevier
The amygdala and orbitofrontal cortex have been implicated in emotion. To understand
these regions better in humans, their effective connectivity with 360 cortical regions was …

The brain's action-mode network

NUF Dosenbach, ME Raichle… - Nature Reviews …, 2025‏ - nature.com
The brain is always intrinsically active, using energy at high rates while cycling through
global functional modes. Awake brain modes are tied to corresponding behavioural states …