[HTML][HTML] Metabolic-associated fatty liver disease and lipoprotein metabolism

J Heeren, L Scheja - Molecular metabolism, 2021‏ - Elsevier
Background Non-alcoholic fatty liver disease, or as recently proposed 'metabolic-associated
fatty liver disease'(MAFLD), is characterized by pathological accumulation of triglycerides …

[HTML][HTML] Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis

CLE Yen, SJ Stone, S Koliwad, C Harris… - Journal of lipid …, 2008‏ - Elsevier
Triacylglycerols (triglycerides)(TGs) are the major storage molecules of metabolic energy
and FAs in most living organisms. Excessive accumulation of TGs, however, is associated …

Role of DGAT enzymes in triacylglycerol metabolism

B Bhatt-Wessel, TW Jordan, JH Miller, L Peng - Archives of biochemistry …, 2018‏ - Elsevier
The esterification of a fatty acyl moiety to diacylglycerol to form triacylglycerol (TAG) is
catalysed by two diacylglycerol O-acyltransferases (DGATs) encoded by genes belonging to …

Acyl-CoA: diacylglycerol acyltransferase: molecular biology, biochemistry and biotechnology

Q Liu, RMP Siloto, R Lehner, SJ Stone… - Progress in lipid …, 2012‏ - Elsevier
Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling

RA Coleman, DG Mashek - Chemical reviews, 2011‏ - ACS Publications
Triacylglycerol (TAG) is the primary unit of energy storage in eukaryotic cells. TAG comprises
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …

Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe–/– mice during disease regression

S Potteaux, EL Gautier, SB Hutchison… - The Journal of clinical …, 2011‏ - jci.org
Experimental models of atherosclerosis suggest that recruitment of monocytes into plaques
drives the progression of this chronic inflammatory condition. Cholesterol-lowering therapy …

Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications

HE Bays, AP Tighe, R Sadovsky… - Expert review of …, 2008‏ - Taylor & Francis
Hypertriglyceridemia is a risk factor for atherosclerotic coronary heart disease. Very high
triglyceride (TG) levels (≥ 500 mg/dl [5.65 mmol/l]) increase the risk of pancreatitis. One …

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism [S]

D Iliopoulos, K Drosatos, Y Hiyama, IJ Goldberg… - Journal of lipid …, 2010‏ - jlr.org
We previously observed that treatment of mice with a dominant negative form of cJun (dn-
cJun) increased the expression of genes involved in lipid metabolism and modulated the …

Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor–null mice with diet-induced insulin resistance

EE Mulvihill, EM Allister, BG Sutherland, DE Telford… - Diabetes, 2009‏ - diabetesjournals.org
OBJECTIVE The global epidemic of metabolic syndrome and its complications demands
rapid evaluation of new and accessible interventions. Insulin resistance is the central …

Fructose consumption: potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance

KL Stanhope, PJ Havel - Current opinion in lipidology, 2008‏ - journals.lww.com
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