The human motor cortex microcircuit: insights for neurodegenerative disease

P McColgan, J Joubert, SJ Tabrizi… - Nature Reviews …, 2020 - nature.com
The human motor cortex comprises a microcircuit of five interconnected layers with different
cell types. In this Review, we use a layer-specific and cell-specific approach to integrate …

[HTML][HTML] Neuroimaging at 7 Tesla: a pictorial narrative review

T Okada, K Fujimoto, Y Fushimi, T Akasaka… - … imaging in medicine …, 2022 - ncbi.nlm.nih.gov
Abstract Neuroimaging using the 7-Tesla (7T) human magnetic resonance (MR) system is
rapidly gaining popularity after being approved for clinical use in the European Union and …

High-resolution quantitative and functional MRI indicate lower myelination of thin and thick stripes in human secondary visual cortex

D Haenelt, R Trampel, S Nasr, JR Polimeni… - elife, 2023 - elifesciences.org
The characterization of cortical myelination is essential for the study of structure-function
relationships in the human brain. However, knowledge about cortical myelination is largely …

7T MP2RAGE for cortical myelin segmentation: Impact of aging

SG Mueller - Plos one, 2024 - journals.plos.org
Background Myelin and iron are major contributors to the cortical MR signal. The aim of this
study was to investigate 1. Can MP2RAGE-derived contrasts at 7T in combination with k …

Segmentation of supragranular and infragranular layers in ultra-high-resolution 7T ex vivo MRI of the human cerebral cortex

X Zeng, O Puonti, A Sayeed, R Herisse, J Mora… - Cerebral …, 2024 - academic.oup.com
Accurate labeling of specific layers in the human cerebral cortex is crucial for advancing our
understanding of neurodevelopmental and neurodegenerative disorders. Building on recent …

[HTML][HTML] Mesoscopic in vivo human T2* dataset acquired using quantitative MRI at 7 Tesla

OF Gulban, S Bollmann, LR Huber, K Wagstyl… - NeuroImage, 2022 - Elsevier
Abstract Mesoscopic (0.1-0.5 mm) interrogation of the living human brain is critical for
advancing neuroscience and bridging the resolution gap with animal models. Despite the …

Combining navigator and optical prospective motion correction for high‐quality 500 μm resolution quantitative multi‐parameter map** at 7T

L Vaculčiaková, K Podranski… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose High‐resolution quantitative multi‐parameter map** shows promise for non‐
invasively characterizing human brain microstructure but is limited by physiological artifacts …

Rhes protein transits from neuron to neuron and facilitates mutant huntingtin spreading in the brain

UN Ramírez-Jarquín, M Sharma, N Shahani, Y Li… - Science …, 2022 - science.org
Rhes (RASD2) is a thyroid hormone–induced gene that regulates striatal motor activity and
promotes neurodegeneration in Huntington disease (HD) and tauopathy. Rhes moves and …

Closed-loop fMRI at the mesoscopic scale of columns and layers: Can we do it and why would we want to?

D Chaimow, R Lorenz… - Philosophical …, 2024 - royalsocietypublishing.org
Technological advances in fMRI including ultra-high magnetic fields (≥ 7 T) and acquisition
methods that increase spatial specificity have paved the way for studies of the human cortex …

Cortical Cross-Frequency Coupling Is Affected by in utero Exposure to Antidepressant Medication

A Tokariev, VC Oberlander, M Videman… - Frontiers in …, 2022 - frontiersin.org
Up to five percent of human infants are exposed to maternal antidepressant medication by
serotonin reuptake inhibitors (SRI) during pregnancy, yet the SRI effects on infants' early …