Short chain fatty acid metabolism in relation to gut microbiota and genetic variability

G Ramos Meyers, H Samouda, T Bohn - Nutrients, 2022 - mdpi.com
It is widely accepted that the gut microbiota plays a significant role in modulating
inflammatory and immune responses of their host. In recent years, the host-microbiota …

Plant hormesis management with biostimulants of biotic origin in agriculture

M Vargas-Hernandez, I Macias-Bobadilla… - Frontiers in plant …, 2017 - frontiersin.org
Over time plants developed complex mechanisms in order to adapt themselves to the
environment. Plant innate immunity is one of the most important mechanisms for the …

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

RS Turner, RG Thomas, S Craft, CH Van Dyck… - Neurology, 2015 - AAN Enterprises
Objective: A randomized, placebo-controlled, double-blind, multicenter 52-week phase 2
trial of resveratrol in individuals with mild to moderate Alzheimer disease (AD) examined its …

Evolution of cellular stress response mechanisms

D Kültz - Journal of Experimental Zoology Part A: Ecological …, 2020 - Wiley Online Library
The cellular stress response (CSR) is pervasive to all domains of life. It has shaped the
interaction between organisms and their environment since the origin of the first cell …

Natural Compounds as Regulators of NLRP3 Inflammasome‐Mediated IL‐1β Production

J Tőzsér, S Benkő - Mediators of Inflammation, 2016 - Wiley Online Library
IL‐1β is one of the main proinflammatory cytokines that regulates a broad range of immune
responses and also participates in several physiological processes. The canonical …

[HTML][HTML] Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration

AS Veskoukis, AM Tsatsakis, D Kouretas - Cell Stress and Chaperones, 2012 - Elsevier
Eukaryotic cells generally function in a reduced state, but an amount of reactive species is
essential for several biochemical processes. The antioxidant network is the defensive …

[HTML][HTML] Hsp70 interactions with membrane lipids regulate cellular functions in health and disease

Z Balogi, G Multhoff, TK Jensen, E Lloyd-Evans… - Progress in lipid …, 2019 - Elsevier
Beyond guarding the cellular proteome the major stress inducible heat shock protein Hsp70
has been shown to interact with lipids. Non-cytosolic Hsp70 stabilizes membranes during …

Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents

JA Menendez, J Joven, G Aragones… - Cell Cycle, 2013 - Taylor & Francis
Aging can be viewed as a quasi-programmed phenomenon driven by the overactivation of
the nutrient-sensing mTOR gerogene. mTOR-driven aging can be triggered or accelerated …

[HTML][HTML] Plasma membranes as heat stress sensors: from lipid-controlled molecular switches to therapeutic applications

Z Török, T Crul, B Maresca, GJ Schütz, F Viana… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The classic heat shock (stress) response (HSR) was originally attributed to protein
denaturation. However, heat shock protein (Hsp) induction occurs in many circumstances …

Beneficial effects of olive oil and Mediterranean diet on cancer physio-pathology and incidence

M Farràs, E Almanza-Aguilera, Á Hernáez… - Seminars in cancer …, 2021 - Elsevier
Virgin olive oil is a characteristic component and the main source of fat of the Mediterranean
diet. It is a mix of high-value health compounds, including monounsaturated fatty acids …