Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Owing to the proximity of the ear canal to the central nervous system, in-ear
electrophysiological systems can be used to unobtrusively monitor brain states. Here, by …

The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Alzheimer's disease (AD) is a progressive neurodegenerative disease in the elderly with
dementia, memory loss, and severe cognitive impairment that imposes high medical costs …

The increasing prevalence of older adults with diabetes has become a major social burden.
Diabetes, frailty, and cognitive dysfunction are closely related to the mechanisms of aging …

Introduction During the last decade, physical activity (PA)(or “exercise”) has been identified
as one of the main modifiable factors that influence the development of Alzheimer's disease …