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Placental hypoxia: What have we learnt from small animal models?
E Siragher, AN Sferruzzi-Perri - Placenta, 2021 - Elsevier
Intrauterine hypoxia is a feature of pregnancy complications, both at high altitude and sea
level. To understand the placental response to reduced oxygen availability, small animal …
level. To understand the placental response to reduced oxygen availability, small animal …
Roles of insulin-like growth factor II in regulating female reproductive physiology
T Muhammad, M Li, J Wang, T Huang, S Zhao… - Science China Life …, 2020 - Springer
The number of growth factors involved in female fertility has been extensively studied, but
reluctance to add essential growth factors in culture media has limited progress in optimizing …
reluctance to add essential growth factors in culture media has limited progress in optimizing …
[HTML][HTML] Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function
The genetic mechanisms that determine the size of the adult pancreas are poorly
understood. Imprinted genes, which are expressed in a parent-of-origin-specific manner, are …
understood. Imprinted genes, which are expressed in a parent-of-origin-specific manner, are …
Loss of imprinting of the Igf2-H19 ICR1 enhances placental endocrine capacity via sex-specific alterations in signalling pathways in the mouse
BRL Aykroyd, SJ Tunster, AN Sferruzzi-Perri - Development, 2022 - journals.biologists.com
Imprinting control region (ICR1) controls the expression of the Igf2 and H19 genes in a
parent-of-origin specific manner. Appropriate expression of the Igf2-H19 locus is …
parent-of-origin specific manner. Appropriate expression of the Igf2-H19 locus is …
Promoter‐specific expression of the imprinted IGF2 gene in bovine oocytes and pre‐implantation embryos
BR Willhelm, E Ticiani, K Campagnolo… - … in Domestic Animals, 2021 - Wiley Online Library
The bovine IGF2 locus is a genomic region with alternative transcripts controlled by five
promoters (P0, P1, P2, P3 and P4). As transcriptional regulation can affect messenger RNA …
promoters (P0, P1, P2, P3 and P4). As transcriptional regulation can affect messenger RNA …
The effect of maternal obesity/GDM and metformin intervention on maternal, placental and fetal health
AS Hufnagel - 2022 - repository.cam.ac.uk
In many populations worldwide over 50% of women have a body mass index above 25.
Therefore, an increasing number of women enter pregnancy overweight or obese. This …
Therefore, an increasing number of women enter pregnancy overweight or obese. This …
Mesenchymal Igf2 is a major paracrine regulator of pancreatic growth and function
The genetic mechanisms that determine the size of the adult pancreas are poorly
understood. Here we demonstrate that many imprinted genes are highly expressed in the …
understood. Here we demonstrate that many imprinted genes are highly expressed in the …