Timing of decompressive surgery of spinal cord after traumatic spinal cord injury: an evidence-based examination of pre-clinical and clinical studies

JC Furlan, V Noonan, DW Cadotte… - Journal of …, 2011 - liebertpub.com
While the recommendations for spine surgery in specific cases of acute traumatic spinal cord
injury (SCI) are well recognized, there is considerable uncertainty regarding the role of the …

The timing of surgical intervention in the treatment of spinal cord injury: a systematic review of recent clinical evidence

MG Fehlings, RG Perrin - Spine, 2006 - journals.lww.com
Study Design. Evidence-based literature review. Objective. To provide updated evidence-
based recommendations regarding spinal cord decompression in patients with acute spinal …

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

JH Badhiwala, JR Wilson, CD Witiw, JS Harrop… - The Lancet …, 2021 - thelancet.com
Background Although there is a strong biological rationale for early decompression of the
injured spinal cord, the influence of the timing of surgical decompression for acute spinal …

Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS)

MG Fehlings, A Vaccaro, JR Wilson, A Singh… - PloS one, 2012 - journals.plos.org
Background There is convincing preclinical evidence that early decompression in the setting
of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early …

The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study

MF Dvorak, VK Noonan, N Fallah, CG Fisher… - Journal of …, 2015 - liebertpub.com
To determine the influence of time from injury to surgery on neurological recovery and length
of stay (LOS) in an observational cohort of individuals with traumatic spinal cord injury (tSCI) …

Early versus late surgery for traumatic spinal cord injury: the results of a prospective Canadian cohort study

JR Wilson, A Singh, C Craven, MC Verrier, B Drew… - Spinal cord, 2012 - nature.com
Study design: A multicenter Canadian cohort study. Objectives: The objective of this study is
to evaluate the impact of early versus late surgical decompression on motor neurological …

Economic impact of traumatic spinal cord injuries in the United States

CH Merritt, MA Taylor, CJ Yelton… - Neuroimmunology and …, 2019 - pmc.ncbi.nlm.nih.gov
Individuals having sustained traumatic spinal cord injury (TSCI) in the United States are
living longer as compared to historical trends, thanks to an ever-evolving understanding of …

Neurological recovery after traumatic cervical spinal cord injury is superior if surgical decompression and instrumented fusion are performed within 8 hours versus 8 to …

M Jug, N Kejžar, M Vesel, S Al Mawed… - Journal of …, 2015 - liebertpub.com
A prospective study was performed to evaluate the impact of surgical decompression (SD)
and instrumented fusion within 8 h versus 8–24 h after injury on neurological recovery after …

Clinical trials targeting secondary damage after traumatic spinal cord injury

ZZ Khaing, JY Chen, G Safarians, S Ezubeik… - International journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) often causes loss of sensory and motor function resulting in a
significant reduction in quality of life for patients. Currently, no therapies are available that …

Current practice in the timing of surgical intervention in spinal cord injury

MG Fehlings, D Rabin, W Sears, DW Cadotte, B Aarabi - Spine, 2010 - journals.lww.com
Study Design. Systematic review of the literature and prospective survey study. Objective. To
characterize expert opinion regarding the timing of surgery for decompression of the injured …