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Role of environmental contaminants in the etiology of Alzheimer's disease: a review
M Yegambaram, B Manivannan… - Current Alzheimer …, 2015 - ingentaconnect.com
Alzheimer's dis ease (AD) is a leading cause of mortality in the developed world with 70%
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …
The role of metallobiology and amyloid‐β peptides in Alzheimer's disease
J. Neurochem.(2012) 120 (Suppl. 1), 149–166. Abstract The biggest risk factor for
Alzheimer's disease is the process of ageing, but the mechanisms that lead to the …
Alzheimer's disease is the process of ageing, but the mechanisms that lead to the …
Exposure to low-dose ambient fine particulate matter PM2.5 and Alzheimer's disease, non-Alzheimer's dementia, and Parkinson's disease in North Carolina
Alzheimer's disease (AD), non-AD dementia, and Parkinson's disease (PD) are increasingly
common in older adults, yet all risk factors for their onset are not fully understood …
common in older adults, yet all risk factors for their onset are not fully understood …
Arsenic induces reactive oxygen species-caused neuronal cell apoptosis through JNK/ERK-mediated mitochondria-dependent and GRP 78/CHOP-regulated …
TH Lu, TJ Tseng, CC Su, FC Tang, CC Yen, YY Liu… - Toxicology letters, 2014 - Elsevier
Abstract Arsenic (As), a well-known high toxic metal, is an important environmental and
industrial contaminant, and it induces oxidative stress, which causes many adverse health …
industrial contaminant, and it induces oxidative stress, which causes many adverse health …
Toxicity mechanisms of arsenic that are shared with neurodegenerative diseases and cognitive impairment: Role of oxidative stress and inflammatory responses
C Escudero-Lourdes - Neurotoxicology, 2016 - Elsevier
Arsenic (As) is a worldwide naturally occurring metalloid. Human chronic exposure to
inorganic As compounds (iAs), which are at the top of hazardous substances (ATSDR …
inorganic As compounds (iAs), which are at the top of hazardous substances (ATSDR …
Counteracting arsenic toxicity: curcumin to the rescue?
Arsenicosis leads to various irreversible damages in several organs and is considered to be
a carcinogen. The effects of chronic arsenic poisoning are a result of an imbalance between …
a carcinogen. The effects of chronic arsenic poisoning are a result of an imbalance between …
Lipid integration in neurodegeneration: an overview of Alzheimer's disease
Various types of lipids and their metabolic products associated with the biological
membrane play a crucial role in signal transduction, modulation, and activation of receptors …
membrane play a crucial role in signal transduction, modulation, and activation of receptors …
Serum zinc is decreased in Alzheimer's disease and serum arsenic correlates positively with cognitive ability
Zinc, copper, and iron aggregate Aβ and accumulate in Alzheimer's disease (AD) plaques.
Some metals are increased in AD vs. control serum. The authors examined levels of 12 …
Some metals are increased in AD vs. control serum. The authors examined levels of 12 …
Attenuation of arsenic neurotoxicity by curcumin in rats
RS Yadav, ML Sankhwar, RK Shukla… - Toxicology and applied …, 2009 - Elsevier
In view of continued exposure to arsenic and associated human health risk including
neurotoxicity, neuroprotective efficacy of curcumin, a polyphenolic antioxidant, has been …
neurotoxicity, neuroprotective efficacy of curcumin, a polyphenolic antioxidant, has been …
Environmental toxins and Alzheimer's disease progression
M Vasefi, E Ghaboolian-Zare, H Abedelwahab… - Neurochemistry …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia, which causes progressive
memory loss and cognitive decline. Effective strategies to treat or prevent remains one of the …
memory loss and cognitive decline. Effective strategies to treat or prevent remains one of the …