Overview of the BioBank Japan Project: Study design and profile
Background: The BioBank Japan (BBJ) Project was launched in 2003 with the aim of
providing evidence for the implementation of personalized medicine by constructing a large …
providing evidence for the implementation of personalized medicine by constructing a large …
The develo** world of DOHaD
K Suzuki - Journal of developmental origins of health and disease, 2018 - cambridge.org
Since its debut in a ground-breaking report by Barker and Osmond in 1986, the concept of
the Developmental Origins of Health and Disease (DOHaD) has been further developed in …
the Developmental Origins of Health and Disease (DOHaD) has been further developed in …
A cross-population atlas of genetic associations for 220 human phenotypes
Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non …
populations and scope of phenotypes. To expand an atlas of genetic associations in non …
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
The overwhelming majority of participants in current genetic studies are of European
ancestry. To elucidate disease biology in the East Asian population, we conducted a …
ancestry. To elucidate disease biology in the East Asian population, we conducted a …
Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese
Personalized medical care focuses on prediction of disease risk and response to
medications. To build the risk models, access to both large-scale genomic resources and …
medications. To build the risk models, access to both large-scale genomic resources and …
jMorp updates in 2020: large enhancement of multi-omics data resources on the general Japanese population
Abstract In the Tohoku Medical Megabank project, genome and omics analyses of
participants in two cohort studies were performed. A part of the data is available at the …
participants in two cohort studies were performed. A part of the data is available at the …
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death,. Fourteen genetic loci have been associated with atrial …
stroke, heart failure, and death,. Fourteen genetic loci have been associated with atrial …
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population
To understand the genetics of type 2 diabetes in people of Japanese ancestry, we
conducted A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases …
conducted A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases …
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Atopic dermatitis is increasing worldwide in correlation with air pollution. Various organic
components of pollutants activate the transcription factor AhR (aryl hydrocarbon receptor) …
components of pollutants activate the transcription factor AhR (aryl hydrocarbon receptor) …
Screen time at age 1 year and communication and problem-solving developmental delay at 2 and 4 years
Importance Whether some domains of child development are specifically associated with
screen time and whether the association continues with age remain unknown. Objective To …
screen time and whether the association continues with age remain unknown. Objective To …