Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

Uncontrolled diabetes results in several metabolic alterations including hyperglycemia.
Indeed, several preclinical and clinical studies have suggested that this condition may …

The anatomy and physiology of the microcirculation in human skin are complex. Normal
cutaneous microcirculation is organized in two parallel plexuses with capillary loops …

Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

Abstract Purpose of Review This article reviewed very recent papers (2016) discussing or
bringing clinical evidences of the possible common pathways leading to diabetic foot …

OBJECTIVE Experimental and epidemiological studies have implicated inflammatory
processes in the pathogenesis of distal sensorimotor polyneuropathy (DSPN), but …

Background Inflammation has been implicated in the pathogenesis of diabetic peripheral
neuropathy (DPN) as suggested in various cross-sectional studies. However, more …

Mitophagy, the cellular process of selectively eliminating damaged mitochondria, plays a
crucial role in maintaining metabolic balance and preventing insulin resistance, both key …

(1) Background: This study examines the survival of patients after their first presentation with
diabetic foot ulcers (DFUs) to the regional Diabetes, Nutrition, and Metabolic Diseases Clinic …