Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

Prospective of 68Ga-radiopharmaceutical development

I Velikyan - Theranostics, 2013 - pmc.ncbi.nlm.nih.gov
Positron Emission Tomography (PET) experienced accelerated development and has
become an established method for medical research and clinical routine diagnostics on …

Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling

MI Tsionou, CE Knapp, CA Foley, CR Munteanu… - RSC …, 2017 - pubs.rsc.org
Gallium-68 (68Ga) is a positron-emitting isotope used for clinical PET imaging of peptide
receptor expression. 68Ga radiopharmaceuticals used in molecular PET imaging consist of …

Cold Kit Labeling: The Future of 68Ga Radiopharmaceuticals?

N Lepareur - Frontiers in Medicine, 2022 - frontiersin.org
Over the last couple of decades, gallium-68 (68Ga) has gained a formidable interest for PET
molecular imaging of various conditions, from cancer to infection, through cardiac …

Bifunctional gallium-68 chelators: Past, present, and future

P Spang, C Herrmann, F Roesch - Seminars in nuclear medicine, 2016 - Elsevier
This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …

[BOOK][B] Handbook on the physics and chemistry of rare earths: including actinides

JCG Bunzli, VK Pecharsky - 2016 - books.google.com
Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous
series of books covering all aspects of rare earth science, including chemistry, life sciences …

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

PRWJ Davey, BM Paterson - Molecules, 2022 - mdpi.com
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both
preclinical and clinical settings with positron emission tomography (PET). The synthesis of …

Responsive gadolinium (III) complex-based small molecule magnetic resonance imaging probes: Design, mechanism and application

Q Meng, M Wu, Z Shang, Z Zhang, R Zhang - Coordination Chemistry …, 2022 - Elsevier
Magnetic resonance imaging (MRI) is a molecular imaging technology that has been widely
adopted in biomedical and clinical diagnostics fields owing to its capability of deep tissue …

Current advances in ligand design for inorganic positron emission tomography tracers 68 Ga, 64 Cu, 89 Zr and 44 Sc

TW Price, J Greenman, GJ Stasiuk - Dalton transactions, 2016 - pubs.rsc.org
A key part of the development of metal based Positron Emission Tomography probes is the
chelation of the radiometal. In this review the recent developments in the chelation of four …