Contemporary techniques and potential transungual drug delivery nanosystems for the treatment of onychomycosis

WH Abd-Elsalam, SM Abouelatta - AAPS PharmSciTech, 2023 - Springer
The humanoid nail is considered an exceptional protective barrier that is formed mainly from
keratin. Onychomycosis is the cause of 50% of nail infections that is generally caused by …

[HTML][HTML] Blending Induced Variations in Poloxamer's/Pluronic's® Gelation: Thermodynamic and Rheological Perspectives

M Qutub, A Tatode, T Premchandani, J Taksande… - JCIS Open, 2024 - Elsevier
Amphiphilic block copolymers (ABCs) are currently significant in pharmaceutical sciences
because of their specific capability to develop various structures that are highly efficient for …

[HTML][HTML] Itraconazole and difluorinated-curcumin containing chitosan nanoparticle loaded hydrogel for amelioration of onychomycosis

P Kesharwani, M Fatima, V Singh, A Sheikh… - Biomimetics, 2022 - mdpi.com
Onychomycosis is a nail infection caused by a fungus, Trichophyton mentagrophytes, that is
responsible for major nail infections. The best method suited for treating such infections …

Gallic acid loaded self-nano emulsifying hydrogel-based drug delivery system against onychomycosis

MS Khan, M Fatima, S Wahab, M Khalid… - …, 2024 - Taylor & Francis
Aim: To developed and investigate gallic acid (GA) loaded self-nanoemulsifying drug
delivery systems (SNEDDS) for treating onychomycosis via transungual route. Materials & …

Intranasal administration of dolutegravir-loaded nanoemulsion-based in situ gel for enhanced bioavailability and direct brain targeting

AB Nair, S Chaudhary, S Jacob, D Patel, P Shinu… - Gels, 2023 - mdpi.com
Dolutegravir's therapeutic effectiveness in the management of neuroAIDS is mainly limited
by its failure to cross the blood–brain barrier. However, lipid-based nanovesicles such as …

[HTML][HTML] Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

AA Al-Shoubki, MH Teaima, R Abdelmonem… - Pharmaceutical Science …, 2024 - Elsevier
This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl
monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions …

[HTML][HTML] Non-invasive peptides delivery using chitosan nanoparticles assembled via scalable microfluidic technology

G Maurizii, S Moroni, JVJ Núnez, G Curzi… - Carbohydrate Polymer …, 2024 - Elsevier
The delivery of peptides via non-invasive administration routes remains a challenge to be
addressed. In this regard, chitosan nanoparticles (CS NPs) have shown promise. However …

A doxorubicin loaded chitosan–poloxamer in situ implant for the treatment of breast cancer

GP Sahoo, VK Rai, D Pradhan, J Halder, TK Rajwar… - RSC …, 2024 - pubs.rsc.org
Breast cancer is a serious concern for many women worldwide. Drug-loaded implants have
shown several benefits over systemic administrations. To provide anti-cancer drugs with …

[HTML][HTML] Gelled Liquid Crystal Nanocarriers for Improved Antioxidant Activity of Resveratrol

A Mancuso, M Tarsitano, R Cavaliere, M Fresta… - Gels, 2023 - mdpi.com
As many natural origin antioxidants, resveratrol is characterized by non-suitable
physicochemical properties for its topical application. To allow its benefits to manifest on …

[HTML][HTML] Gels as Promising Delivery Systems: Physicochemical Property Characterization and Recent Applications

E Wang, Z Qi, Y Cao, R Li, J Wu, R Tang, Y Gao, R Du… - Pharmaceutics, 2025 - mdpi.com
Gels constitute a versatile class of materials with considerable potential for applications in
both technical and medical domains. Physicochemical property characterization is a critical …