Background: Intravenous (IV) pulses of methylprednisolone (MEP) commonly are used to
treat severe manifestations of systemic lupus erythematosus (SLE). However, despite wide …

The pharmacological armamentarium for the treatment of SLE is expanding and a number of
novel therapies are currently under investigation. In spite of this, steroid therapy remains the …

Background: Uncertainty exists about the efficacy and toxicity of bolus therapy with
methylprednisolone or of the combination of methylprednisolone and cyclophosphamide in …

High dose pulse intravenous steroids with 1 g of methylprednisolone (MEP) given daily,
usually for three days, is an accepted practice to treat severe manifestations of systemic …

The prognosis for children with chronic interstitial lung disease is poor and the mortality rate
is high, especially in infants. This explains the many therapeutical protocols which have …

(GREs). This interaction leads to up-regulation or down-regulation of specific genes that
encode proteins responsible for the action of GCs, such as many cytokines and adhesion …

Idiopathic pulmonary hemosiderosis (IPH) is an extremely rare cause of massive pulmonary
hemorrhage in children. During the acute phase, death due to massive alveolar hemorrhage …

Objective The objective is to determine the 30-day hospital readmission rate following a
hospitalization due to pediatric lupus nephritis of recent onset and characterize the risk …

Abstract Treatment in systemic lupus erythematosus (SLE) must be adjusted to the current
level of disease activity and the course of the disease. The spectrum of established …

A validação da técnica analítica para dosagem da metilprednisolona (MP) e seu éster
succinato sódico (MPSS) em plasma humano de pacientes lúpicos (LES) foi desenvolvida …