[HTML][HTML] Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles
Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …
Molecular physiology of TRPV channels: controversies and future challenges
The ability to detect stimuli from the environment plays a pivotal role in our survival. The
molecules that allow the detection of such signals include ion channels, which are proteins …
molecules that allow the detection of such signals include ion channels, which are proteins …
A pentameric TRPV3 channel with a dilated pore
Transient receptor potential (TRP) channels are a large, eukaryotic ion channel superfamily
that control diverse physiological functions, and therefore are attractive drug targets,,,–. More …
that control diverse physiological functions, and therefore are attractive drug targets,,,–. More …
An introduction to TRP channels
▪ Abstract The aim of this review is to provide a basic framework for understanding the
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
function of mammalian transient receptor potential (TRP) channels, particularly as they have …
Transient receptor potential cation channels in disease
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
The role of transient receptor potential cation channels in Ca2+ signaling
M Gees, B Colsoul, B Nilius - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …
channels are cation channels, mostly permeable to both monovalent and divalent cations …
Trp ion channels and temperature sensation
A Dhaka, V Viswanath, A Patapoutian - Annu. Rev. Neurosci., 2006 - annualreviews.org
The abilities to sense environmental and internal temperatures are required for survival,
both for maintenance of homeostasis and for avoidance of tissue-damaging noxious …
both for maintenance of homeostasis and for avoidance of tissue-damaging noxious …
TRP channels: an overview
The TRP (“transient receptor potential”) family of ion channels now comprises more than 30
cation channels, most of which are permeable for Ca2+, and some also for Mg2+. On the …
cation channels, most of which are permeable for Ca2+, and some also for Mg2+. On the …
Calcium and cancer: targeting Ca2+ transport
Ca2+ is a ubiquitous cellular signal. Altered expression of specific Ca2+ channels and
pumps are characterizing features of some cancers. The ability of Ca2+ to regulate both cell …
pumps are characterizing features of some cancers. The ability of Ca2+ to regulate both cell …
[HTML][HTML] A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome
Human monogenic pain syndromes have provided important insights into the molecular
mechanisms that underlie normal and pathological pain states. We describe an autosomal …
mechanisms that underlie normal and pathological pain states. We describe an autosomal …