Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Recent progress in targeted delivery vectors based on biomimetic nanoparticles

L Chen, W Hong, W Ren, T Xu, Z Qian… - Signal transduction and …, 2021 - nature.com
Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis

L Rao, L Wu, Z Liu, R Tian, G Yu, Z Zhou… - Nature …, 2020 - nature.com
Effectively activating macrophages against cancer is promising but challenging. In particular,
cancer cells express CD47, a 'don't eat me'signal that interacts with signal regulatory protein …

Cell membrane-coated mimics: a methodological approach for fabrication, characterization for therapeutic applications, and challenges for clinical translation

V Chugh, K Vijaya Krishna, A Pandit - ACS nano, 2021 - ACS Publications
Cell membrane-coated (CMC) mimics are micro/nanosystems that combine an isolated cell
membrane and a template of choice to mimic the functions of a cell. The design exploits its …

Chemically engineering cells for precision medicine

Y Wang, Z Li, F Mo, TJ Chen-Mayfield, A Saini… - Chemical Society …, 2023 - pubs.rsc.org
Cell-based therapy holds great potential to address unmet medical needs and revolutionize
the healthcare industry, as demonstrated by several therapeutics such as CAR-T cell …

Cell membrane-camouflaged nanocarriers with biomimetic deformability of erythrocytes for ultralong circulation and enhanced cancer therapy

Y Miao, Y Yang, L Guo, M Chen, X Zhou, Y Zhao… - ACS …, 2022 - ACS Publications
Despite considerable advancements in cell membrane-camouflaged nanocarriers to
leverage natural cell functions, artificial nanocarriers that can accurately mimic both the …

Recent advances of cell membrane‐coated nanomaterials for biomedical applications

WL Liu, MZ Zou, SY Qin, YJ Cheng… - Advanced Functional …, 2020 - Wiley Online Library
Surface modification of nanomaterials is essential for their biomedical applications owing to
their passive immune clearance and damage to reticuloendothelial systems. Recently, a cell …

Cell membrane coated nanocarriers-an efficient biomimetic platform for targeted therapy

P Dash, AM Piras, M Dash - Journal of controlled release, 2020 - Elsevier
Targeted therapy approaches have become the core of modern translational science and as
an intriguing field, it is the solution of the conventional drug delivery problems that were …

Biomimetic cell membrane‐coated poly(lactic‐co‐glycolic acid) nanoparticles for biomedical applications

N Jan, A Madni, S Khan, H Shah… - Bioengineering & …, 2023 - Wiley Online Library
Poly (lactic‐co‐glycolic acid)(PLGA) nanoparticles (NPs) are commonly used for drug
delivery because of their favored biocompatibility and suitability for sustained and controlled …

Dacarbazine-primed carbon quantum dots coated with breast cancer cell-derived exosomes for improved breast cancer therapy

P Tiwari, RP Shukla, K Yadav, N Singh… - Journal of Controlled …, 2024 - Elsevier
Imprecise targeting of chemotherapeutic drugs often leads to severe toxicity during breast
cancer therapy. To address this issue, we have devised a strategy to load dacarbazine (DC) …