Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …
[HTML][HTML] Free fatty acid receptors in health and disease
Fatty acids are metabolized and synthesized as energy substrates during biological
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
responses. Long-and medium-chain fatty acids derived mainly from dietary triglycerides, and …
Tumour extracellular vesicles and particles induce liver metabolic dysfunction
Cancer alters the function of multiple organs beyond those targeted by metastasis,. Here we
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …
[HTML][HTML] The carbohydrate-insulin model: a physiological perspective on the obesity pandemic
According to a commonly held view, the obesity pandemic is caused by overconsumption of
modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary …
modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary …
Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …
Competing paradigms of obesity pathogenesis: energy balance versus carbohydrate-insulin models
The obesity pandemic continues unabated despite a persistent public health campaign to
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …
decrease energy intake (“eat less”) and increase energy expenditure (“move more”). One …
Linking gut microbiota and inflammation to obesity and insulin resistance
Obesity and insulin resistance are the major predisposing factors to comorbidities, such as
Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative …
Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative …
Anti-inflammatory nutrients and obesity-associated metabolic-inflammation: state of the art and future direction
Growing evidence supports the hypothesis that dietary factors may play a role in systemic
low-grade chronic inflammation. Summary evidence from randomized controlled trials has …
low-grade chronic inflammation. Summary evidence from randomized controlled trials has …
Diet and inflammation in cognitive ageing and Alzheimer's disease
AM McGrattan, B McGuinness, MC McKinley… - Current nutrition …, 2019 - Springer
Abstract Purpose of Review Nutrition is known to modulate the immune system and may
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …
alter neuroinflammatory processes implicated in the pathogenesis of Alzheimer's disease …
[HTML][HTML] Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease
S Pugazhenthi, L Qin, PH Reddy - … acta (BBA)-molecular basis of disease, 2017 - Elsevier
Cognitive decline in chronic diabetic patients is a less investigated topic. Diabetes and
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …
obesity are among the modifiable risk factors for Alzheimer's disease (AD), the most …