As an intracellular pattern recognition receptor (PPR), the nucleotide-binding
oligomerization domain-containing protein 2 (NOD2) triggers a cascade of immune …

Activation of inflammatory signaling pathways is of central importance in the pathogenesis of
alcoholic liver disease (ALD) and nonalcoholic steatohepatitis (NASH). Nod-like receptors …

Objective Nucleotide‐binding oligomerization domain‐containing protein 2 (NOD2) gene
mutations are known to be an important risk factor in the pathogenesis of Crohn's disease …

Background In short bowel syndrome, epithelial surface loss results in impaired nutrient
absorption and may lead to intestinal insufficiency or intestinal failure. Nucleotide …

Protein O-GlcNAcylation is a dynamic post-translational protein modification that regulates
fundamental cellular functions in both normal physiology and diseases. The levels of protein …

Background Short bowel syndrome results from extensive small bowel resection and
induces adaptation of the remaining intestine. Ileocecal resection (ICR) is the most frequent …

Inflammatory bowel disease and Crohn's disease in particular, is a common cause of
intestinal failure. Current therapeutic options include home parenteral nutrition and intestinal …

Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) gene mutations are
a risk factor for Crohn's disease and also associated with worse outcome in short bowel …

Objectives: Intestinal transplantation is an option for permanent intestinal failure with
parenteral nutrition intolerance. We sought to determine long-term intestinal graft survival in …

Stimulation by luminal nutrients as well as prophylaxis against and treatment of (nutritional)
complications are the cornerstones of adaptation to the short bowel situation. Based on …