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Cell transplantation therapy for spinal cord injury
Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …
From basics to clinical: a comprehensive review on spinal cord injury
Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …
individuals each year. Over the past decades an enormous progress has been made in our …
Therapeutic repair for spinal cord injury: combinatory approaches to address a multifaceted problem
The recent years saw the advent of promising preclinical strategies that combat the
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
devastating effects of a spinal cord injury (SCI) that are progressing towards clinical trials …
Neural tissue engineering: strategies for repair and regeneration
▪ Abstract Nerve regeneration is a complex biological phenomenon. In the peripheral
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …
nervous system, nerves can regenerate on their own if injuries are small. Larger injuries …
Safety of autologous human schwann cell transplantation in subacute thoracic spinal cord injury
The rationale for implantation of autologous human Schwann cells (SCs) in persons with
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …
A systematic review of cellular transplantation therapies for spinal cord injury
Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …
Concepts and methods for the study of axonal regeneration in the CNS
Progress in the field of axonal regeneration research has been like the process of axonal
growth itself: there is steady progress toward reaching the target, but there are episodes of …
growth itself: there is steady progress toward reaching the target, but there are episodes of …
Combinatorial therapies after spinal cord injury: how can biomaterials help?
Traumatic spinal cord injury (SCI) results in an immediate loss of motor and sensory function
below the injury site and is associated with a poor prognosis. The inhibitory environment that …
below the injury site and is associated with a poor prognosis. The inhibitory environment that …
Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats
O Rapalino, O Lazarov-Spiegler, E Agranov… - Nature medicine, 1998 - nature.com
Postinjury recovery in most tissues requires an effective dialog with macrophages; however,
in the mammalian central nervous system, this dialog may be restricted (possibly due to its …
in the mammalian central nervous system, this dialog may be restricted (possibly due to its …
Repair of adult rat corticospinal tract by transplants of olfactory ensheathing cells
Y Li, PM Field, G Raisman - Science, 1997 - science.org
The upper cervical corticospinal tract was transected on one side in adult rats. A suspension
of ensheathing cells cultured from adult rat olfactory bulb was injected into the lesion site …
of ensheathing cells cultured from adult rat olfactory bulb was injected into the lesion site …