SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased
risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden …

Recurrent pregnancy loss is a common problem in the reproductive age population of
women. It can be caused by many different conditions. This problem is addressed in …

Despite years of research, miscarriage, particularly when recurrent, continues to pose a
medical challenge. An embryo chromosomal error is responsible for 50–60% of recurrent …

Studies have indicated that thrombophilic genes polymorphisms are associated with
recurrent pregnancy loss (RPL) in the Iranian population. We aimed to evaluate the precise …

Purpose Recurrent pregnancy loss (RPL) is affecting 1–4% of women who conceive
approximately, and no cause could be found in more than 50% of women suffering from …

Miscarriage is the most common complication in pregnancy. Considering the importance of
the problem thrombophilia in pregnant women and its association with recurrent pregnancy …

Background Thrombophilia is a group of disorders that result in a blood hypercoagulable
state and induce thrombosis, which was found widely existed in recurrent pregnancy loss …

Plasminogen activator inhibitor type 1 (PAI-1) is a main inhibitor of fibrinolysis. The PAI-1
gene (SERPINE1) harbors genetic variants with the potential of modifying plasma levels of …

Background The association between plasminogen activator inhibitor-1 (PAI-1) 4G/5G
polymorphism and recurrent pregnancy loss (RPL) risk is still contradictory. We thus …

Aim To investigate association of factor V Leiden, prothrombin G20210A, MTHFR C677T
and PAI-1 4G/5G polymorphisms with recurrent pregnancy loss in Bosnian women. Methods …