Novel microneedle platforms for the treatment of wounds by drug delivery: a review

H An, Z Gu, Z Huang, T Huo, Y Xu, Y Dong… - Colloids and Surfaces B …, 2024 - Elsevier
The management and treatment of wounds are complex and pose a substantial financial
burden to the patient. However, the complex environment of wounds leads to inadequate …

Recent advances in transdermal insulin delivery technology: A review

H Li, Y Shi, X Ding, C Zhen, G Lin, F Wang… - International Journal of …, 2024 - Elsevier
Transdermal drug delivery refers to the administration of drugs through the skin, after which
the drugs can directly act on or circulate through the body to the target organs or cells and …

Photothermal microneedle patch loaded with antimicrobial peptide/MnO2 hybrid nanoparticles for chronic wound healing

G Wang, W Wang, Z Chen, T Hu, L Tu, X Wang… - Chemical Engineering …, 2024 - Elsevier
Chronic wound with complex clinical characteristics poses a significant challenge
worldwide. Bioactive and stimulus responsive microneedle patch (MNP) has recently …

Chlorella‐Loaded Antibacterial Microneedles for Microacupuncture Oxygen Therapy of Diabetic Bacterial Infected Wounds

S Gao, Y Rao, X Wang, Q Zhang, Z Zhang… - Advanced …, 2024 - Wiley Online Library
Hypoxia and infection are urgent clinical problems in chronic diabetic wounds. Herein, living
Chlorella‐loaded poly (ionic liquid)‐based microneedles (PILMN‐Chl) are constructed for …

Composite microneedles loaded with Astragalus membranaceus polysaccharide nanoparticles promote wound healing by curbing the ROS/NF-κB pathway to …

X Liu, C Guo, W Yang, W Wang, N Diao, M Cao… - Carbohydrate …, 2024 - Elsevier
The healing of chronic diabetic wounds remains a formidable challenge in modern times. In
this study, a novel traditional Chinese medicine microneedle patch was designed based on …

Opportunities and challenges of microneedle electrochemical sensors for interstitial fluid detection

Y Dong, S Mao, S Chen, J Ma… - TrAC Trends in …, 2024 - Elsevier
Microneedle (MN) electrochemical sensors offer new strategies for personalized medicine
and point-to-point medical testing, providing new opportunities for disease diagnosis and …

Self‐Sterilizing Microneedle Sensing Patches for Machine Learning‐Enabled Wound pH Visual Monitoring

J **ao, Z Zhou, G Zhong, T Xu… - Advanced Functional …, 2024 - Wiley Online Library
The skin, as the body's largest organ, is closely linked to an individual's health. Delayed
diagnosis and treatment of skin infections can lead to complications such as non‐healing …

[HTML][HTML] Glucose oxidase: An emerging multidimensional treatment option for diabetic wound healing

Y Liao, Z Zhang, Y Zhao, S Zhang, K Zha, L Ouyang… - Bioactive Materials, 2025 - Elsevier
The healing of diabetic skin wounds is a complex process significantly affected by the
hyperglycemic environment. In this context, glucose oxidase (GOx), by catalyzing glucose to …

Recent progress of microneedles in transdermal immunotherapy: a review

X Ai, J Yang, Z Liu, T Guo, N Feng - International Journal of Pharmaceutics, 2024 - Elsevier
Since human skin is an immune organ, a large number of immune cells are distributed in the
epidermis and the dermis of the skin. Transdermal immunotherapy shows great therapeutic …

Multifunctional Hydrogel Microneedle Patches Modulating Oxi‐inflamm‐aging for Diabetic Wound Healing

S Tian, J Mei, L Zhang, S Wang, Y Yuan, J Li, H Liu… - Small, 2024 - Wiley Online Library
Oxidative stress, chronic inflammation, and immune senescence are important pathologic
factors in diabetic wound nonhealing. This study loads taurine (Tau) into cerium dioxide …