Next generation immuno-oncology biomarkers in gastrointestinal cancer: what does the future hold?

H Abushukair, O Ababneh, A Al-Bzour… - Expert Review of …, 2023 - Taylor & Francis
Introduction Gastrointestinal (GI) cancers pose a significant health burden worldwide,
necessitating advancements in diagnostic and treatment approaches. One promising …

[HTML][HTML] The necroptosis signature and molecular mechanism of lung squamous cell carcinoma

GQ Song, HM Wu, KJ Ji, TL He, YM Duan… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Background: Given the poor prognosis of lung squamous cell carcinoma (LUSC), the aim of
this study was to screen for new prognostic biomarkers. Methods: The TGCA_LUSC dataset …

[HTML][HTML] KIF3C: an emerging biomarker with prognostic and immune implications across pan-cancer types and its experiment validation in gastric cancer

Q Zhong, W Hong, L **ong - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Abstract Kinesin Family Member 3C (KIF3C) assumes a crucial role in various biological
processes of specific human cancers. Nevertheless, there exists a paucity of systematic …

IFN-α/β/IFN-γ/IL-15 pathways identify GBP1-expressing tumors with an immune-responsive phenotype

L Wang, Y Wei, Z **, F Liu, X Li, X Zhang, X Bai… - Clinical and …, 2024 - Springer
Immunotherapy is widely used in cancer treatment; however, only a subset of patients
responds well to it. Significant efforts have been made to identify patients who will benefit …

[HTML][HTML] PD-L1 as a Biomarker in Gastric Cancer Immunotherapy

Y Cho, S Ahn, KM Kim - Journal of Gastric Cancer, 2024 - pmc.ncbi.nlm.nih.gov
Combining chemotherapy with immune checkpoint inhibitors (ICIs) that target the
programmed death-1 (PD-1) protein has been shown to be a clinically effective first-line …

Stemness Landscape and Its Clinical Implications in Hepatocellular Carcinoma

X Gong, L Bao, Y Chen, K Qu, S Zhou, X Chen, Q Pang - 2023 - researchsquare.com
Background: It is generally accepted that hepatocarcinoma (HCC) originates from cancer
stem cells (CSCs), which are responsible for HCC progression, metastasis and therapy …

[HTML][HTML] The tumor immune composition of mismatch repair deficient and Epstein-Barr virus-positive gastric cancer: A systematic review

J Bos, TS Groen-van Schooten, CP Brugman… - Cancer Treatment …, 2024 - Elsevier
Background Gastric cancer (GC), known for its unfavorable prognosis, has been classified in
four distinct molecular subtypes. These subtypes not only exhibit differences in their genome …