Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …

Atherosclerotic cardiovascular disease (ASCVD) proceeds through a series of stages:
initiation, progression (or regression), and complications. By integrating known biology …

Objective Heightened inflammation, dysregulated immunity, and thrombotic events are
characteristic of hospitalized COVID‐19 patients. Given that platelets are key regulators of …

Although infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
pleiotropic and systemic effects in some individuals,–, many others experience milder …

Intravascular neutrophils and platelets collaborate in maintaining host integrity, but their
interaction can also trigger thrombotic complications. We report here that cooperation …

Platelets are key mediators of atherothrombosis, yet, limited tools exist to identify individuals
with a hyperreactive platelet phenotype. In this study, we investigate the association of …

Abstract Novel coronavirus disease 2019 (COVID-19) is associated with a hypercoagulable
state, characterized by abnormal coagulation parameters and by increased incidence of …

Background: Atherosclerotic cardiovascular diseases are characterized by a dysregulated
inflammatory and thrombotic state, leading to devastating complications with increased …

Anucleate platelets, long viewed as merely cell fragments with a limited repertoire of rapid-
acting hemostatic functions, are now recognized to have a complex and dynamic …

Background Platelets circulate in the blood of healthy individuals for approximately 7–10
days regulated by finely balanced processes of production and destruction. As platelets are …