The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Integrin receptors are the main molecular link between cells and the extracellular matrix
(ECM) as well as mediating cell–cell interactions. Integrin–ECM binding triggers the …

The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

The tumor microenvironment (TME) controls tumor progression and maintenance.
Accordingly, tumor-centric cancer treatment must adjust to being more holistic and TME …

The extracellular matrix (ECM) is pivotal in modulating tumor progression. Besides
chemically stimulating tumor cells, it also offers physical support that orchestrates the …

The tumor extracellular matrix (ECM) provides physical support and influences tumor
development, metastasis, and the tumor microenvironment, creating barriers to immune drug …

The geometric reconfigurations in three-dimensional morphable structures have a wide
range of applications in flexible electronic devices and smart systems with unusual …

The extracellular matrix (ECM) of solid tumors impacts the antitumor activities of CD8+ T and
natural killer (NK) cells in a variety of ways. Cell motility is restricted by the tumor ECM which …

Background: Rheumatoid arthritis (RA) is a chronic disabling inflammatory disease that
causes synovial angiogenesis in an invasive manner and leads to joint destruction …

Abstract 3D in vitro tumor models have recently been investigated as they can recapitulate
key features in the tumor microenvironment. Reconstruction of a biomimetic scaffold is …