Satellite cells and the muscle stem cell niche
Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
Making muscle: skeletal myogenesis in vivo and in vitro
Skeletal muscle is the largest tissue in the body and loss of its function or its regenerative
properties results in debilitating musculoskeletal disorders. Understanding the mechanisms …
properties results in debilitating musculoskeletal disorders. Understanding the mechanisms …
Function of the myogenic regulatory factors Myf5, MyoD, Myogenin and MRF4 in skeletal muscle, satellite cells and regenerative myogenesis
PS Zammit - Seminars in cell & developmental biology, 2017 - Elsevier
Discovery of the myogenic regulatory factor family of transcription factors MYF5, MYOD,
Myogenin and MRF4 was a seminal step in understanding specification of the skeletal …
Myogenin and MRF4 was a seminal step in understanding specification of the skeletal …
Building muscle: molecular regulation of myogenesis
The genesis of skeletal muscle during embryonic development and postnatal life serves as a
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …
paradigm for stem and progenitor cell maintenance, lineage specification, and terminal …
[HTML][HTML] The myogenic regulatory factors, determinants of muscle development, cell identity and regeneration
JM Hernández-Hernández, EG García-González… - Seminars in cell & …, 2017 - Elsevier
Abstract The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are
members of the basic helix-loop-helix family of transcription factors that control the …
members of the basic helix-loop-helix family of transcription factors that control the …
[PDF][PDF] Satellite cells and skeletal muscle regeneration
Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …
Asymmetric self-renewal and commitment of satellite stem cells in muscle
Satellite cells play a central role in mediating the growth and regeneration of skeletal
muscle. However, whether satellite cells are stem cells, committed progenitors, or …
muscle. However, whether satellite cells are stem cells, committed progenitors, or …
Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage
F Relaix, PS Zammit - Development, 2012 - journals.biologists.com
Following their discovery in 1961, it was speculated that satellite cells were dormant
myoblasts, held in reserve until required for skeletal muscle repair. Evidence for this …
myoblasts, held in reserve until required for skeletal muscle repair. Evidence for this …
Intrinsic and extrinsic mechanisms regulating satellite cell function
Muscle stem cells, termed satellite cells, are crucial for skeletal muscle growth and
regeneration. In healthy adult muscle, satellite cells are quiescent but poised for activation …
regeneration. In healthy adult muscle, satellite cells are quiescent but poised for activation …
The skeletal muscle satellite cell: the stem cell that came in from the cold
PS Zammit, TA Partridge… - … of Histochemistry & …, 2006 - journals.sagepub.com
The muscle satellite cell was first described and actually named on the basis of its anatomic
location under the basement membrane surrounding each myofiber. For many years …
location under the basement membrane surrounding each myofiber. For many years …