The use of antibiotics has enabled the successful treatment of bacterial infections, saving the
lives and improving the health of many patients worldwide. However, the emergence and …

Background During the last six decades, extensive use of antibiotics has selected resistant
strains, increasing the rate of fatal infectious diseases, and exerting an economic burden on …

Antibiotic resistance is a major problem in Salmonella enterica serovar Typhi, the causative
agent of typhoid. Multidrug-resistant (MDR) isolates are prevalent in parts of Asia and Africa …

Salmonella infection causes morbidity and mortality throughout the world with the host
immune response varying depending on whether the infection is acute and limited, or …

Background Antimicrobial resistance (AMR) is an increasing threat to global health. There
are> 14 million cases of enteric fever every year and> 135,000 deaths. The disease is …

Background Pakistan is currently facing the largest outbreak of ceftriaxone-resistant
Salmonella enterica serotype Typhi described to date. Here we aimed to report the outbreak …

Understanding patterns and trends of antimicrobial resistance (AMR) in Salmonella Typhi
can guide empiric treatment recommendations and contribute to country decisions about …

Appropriate prescribing practices for fluoroquinolones, as well as all antimicrobial agents,
are essential as evolving resistance patterns are considered, additional treatment …

Background Clinicians have limited therapeutic options for enteric as a result of increasing
antimicrobial resistance, and therefore typhoid vaccination is recommended as a preventive …

Abstract Background The Aga Khan University clinical microbiology laboratory identified an
outbreak of ceftriaxone-resistant Salmonella Typhi in Hyderabad, Pakistan, through …