Prevention, treatment and cure of HIV infection

RJ Landovitz, H Scott, SG Deeks - Nature Reviews Microbiology, 2023 - nature.com
The development of antiretroviral therapy for the prevention and treatment of HIV infection
has been marked by a series of remarkable successes. However, the efforts to develop a …

Barriers to the wider use of pre-exposure prophylaxis in the United States: a narrative review

KH Mayer, A Agwu, D Malebranche - Advances in therapy, 2020 - Springer
Antiretroviral pre-exposure prophylaxis (PrEP) to prevent HIV transmission was first
approved by the US Food and Drug Administration in 2012. Despite correlations of …

Cabotegravir for the prevention of HIV-1 in women: results from HPTN 084, a phase 3, randomised clinical trial

S Delany-Moretlwe, JP Hughes, P Bock, SG Ouma… - The Lancet, 2022 - thelancet.com
Background Oral pre-exposure prophylaxis has been introduced in more than 70 countries,
including many in sub-Saharan Africa, but women experience considerable barriers to daily …

Cabotegravir for HIV prevention in cisgender men and transgender women

RJ Landovitz, D Donnell, ME Clement… - … England Journal of …, 2021 - Mass Medical Soc
Background Safe and effective long-acting injectable agents for preexposure prophylaxis
(PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options …

Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a …

KH Mayer, JM Molina, MA Thompson, PL Anderson… - The Lancet, 2020 - thelancet.com
Background Tenofovir alafenamide shows high antiviral efficacy and improved renal and
bone safety compared with tenofovir disoproxil fumarate when used for HIV treatment. Here …

Clinical targeting of HIV capsid protein with a long-acting small molecule

JO Link, MS Rhee, WC Tse, J Zheng, JR Somoza… - Nature, 2020 - nature.com
Oral antiretroviral agents provide life-saving treatments for millions of people living with HIV,
and can prevent new infections via pre-exposure prophylaxis,,,–. However, some people …

[HTML][HTML] HIV preexposure prophylaxis, by race and ethnicity—United States, 2014–2016

AH Ya-lin - MMWR. Morbidity and mortality weekly report, 2018 - cdc.gov
HIV Preexposure Prophylaxis, by Race and Ethnicity — United States, 2014–2016 | MMWR Skip
directly to site content Skip directly to page options Skip directly to AZ link Centers for Disease …

Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study

JM Molina, J Ghosn, L Assoumou, C Delaugerre… - The lancet HIV, 2022 - thelancet.com
Background There are few data available regarding the use of on-demand pre-exposure
prophylaxis (PrEP) for HIV prevention. We aimed to assess PrEP effectiveness, adherence …

Oral pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all …

EO Murchu, L Marshall, C Teljeur, P Harrington… - BMJ open, 2022 - bmjopen.bmj.com
Objective To conduct a systematic review and meta-analysis of randomised controlled trials
(RCTs) of the effectiveness and safety of oral pre-exposure prophylaxis (PrEP) to prevent …

HIV infection and AIDS in sub-Saharan Africa: current status, challenges and opportunities

ABM Kharsany, QA Karim - The open AIDS journal, 2016 - pmc.ncbi.nlm.nih.gov
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and
substantial declines in AIDS related deaths largely attributable to the survival benefits of …