Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets
The rationale for vitamin, mineral, and cofactor treatment in the precision medical care of autism spectrum disorder
Children with autism spectrum disorder may exhibit nutritional deficiencies due to reduced
intake, genetic variants, autoantibodies interfering with vitamin transport, and the …
intake, genetic variants, autoantibodies interfering with vitamin transport, and the …
Phase separation and zinc-induced transition modulate synaptic distribution and association of autism-linked CTTNBP2 and SHANK3
Many synaptic proteins form biological condensates via liquid-liquid phase separation
(LLPS). Synaptopathy, a key feature of autism spectrum disorders (ASD), is likely relevant to …
(LLPS). Synaptopathy, a key feature of autism spectrum disorders (ASD), is likely relevant to …
Analysis of whole blood and urine trace elements in children with autism spectrum disorders and autistic behaviors
G Zhao, S Liu, X Gan, J Li, X Wu, S Liu, Y **… - Biological trace element …, 2023 - Springer
The relationship between trace elements and neurological development is an emerging
research focus. We performed a case–control study to explore (1) the differences of 13 trace …
research focus. We performed a case–control study to explore (1) the differences of 13 trace …
Shankopathies in the develo** brain in autism spectrum disorders
The SHANK family of proteins play critical structural and functional roles in the postsynaptic
density (PSD) at excitatory glutamatergic synapses. Through their multidomain structure they …
density (PSD) at excitatory glutamatergic synapses. Through their multidomain structure they …
Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice
E Atanasova, AP Arévalo, I Graf, R Zhang, J Bockmann… - Molecular Autism, 2023 - Springer
Background Autism spectrum disorder (ASD) is mainly characterized by deficits in social
interaction and communication and repetitive behaviors. Known causes of ASD are …
interaction and communication and repetitive behaviors. Known causes of ASD are …
Metal profiles in autism spectrum disorders: A crosstalk between toxic and essential metals
A Błażewicz, AM Grabrucker - International Journal of Molecular Sciences, 2022 - mdpi.com
Since hundreds of years ago, metals have been recognized as impacting our body's
physiology. As a result, they have been studied as a potential cure for many ailments as well …
physiology. As a result, they have been studied as a potential cure for many ailments as well …