ICAM-1 is a cell surface glycoprotein and an adhesion receptor that is best known for
regulating leukocyte recruitment from circulation to sites of inflammation. However, in …

A central function of the vascular endothelium is to serve as a barrier between the blood and
the surrounding tissue of the body. At the same time, solutes and cells have to pass the …

Malaria caused by the Plasmodium family of parasites, especially P. falciparum and P. vivax,
is a major health problem in many countries in the tropical and subtropical regions of the …

Fibrosis of the glomerular and tubulointerstitial compartments is a common feature of chronic
kidney disease leading to end-stage renal failure. This fibrotic process involves a number of …

The skin has a solid protective system that includes the stratum corneum as the primary
barrier and a complete antioxidant defence system to maintain the skin's normal redox …

Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis
which is critical in physiological and pathophysiological procedures. However, how …

Simple Summary Intercellular adhesion molecule 1 (ICAM-1) is a protein produced by cells
in blood vessel walls, as well as many other cell types. It localizes to the surface of these …

Background During neuroinflammation many chemokines alter the function of the blood-
brain barrier (BBB) that regulates the entry of macromolecules and immune cells into the …

Abstract Intercellular adhesion molecule-1 (ICAM-1) is a versatile molecule that plays a
critical role in various physiological and pathological processes, particularly in tumor …

Group 2 innate lymphoid cells (ILC2s) are emerging as key players in the pathogenesis of
allergic airway inflammation. The mechanisms regulating ILC2, however, are not fully …