Carba PBP: a novel penicillin-binding protein-based lateral flow assay for rapid phenotypic detection of carbapenemase-producing Enterobacterales

Z Lu, X Wang, L Ma, L Dou, X Zhao, J Tao… - Journal of Clinical …, 2024 - Am Soc Microbiol
Rapid phenotypic detection assays, including Carba NP and its variants, are widely applied
for clinical diagnosis of carbapenemase-producing Enterobacterales (CPE). However, these …

Cyclodextrins as multifunctional excipients: Influence of inclusion into β-cyclodextrin on physicochemical and biological properties of tebipenem pivoxil

M Paczkowska, D Szymanowska-Powałowska… - PLoS …, 2019 - journals.plos.org
A novel approach for drug design based on the oral carbapenem analog tebipenem pivoxil
(TP) has been proposed. The formation of the tebipenem pivoxil-β-cyclodextrin (TP-β-CD) …

Facile HPTLC-densitometric determination of ertapenem and paracetamol in pharmaceuticals and rabbit plasma with pharmacokinetic insights

MI Gadallah, HRH Ali, HF Askal, GA Saleh - Microchemical Journal, 2019 - Elsevier
Simultaneous chromatographic determination of both ertapenem (ERP) and paracetamol
(PCL) was achieved for the first time via a new HPTLC-densitometric method. The …

Solid-state stability study of meropenem–solutions based on spectrophotometric analysis

J Cielecka-Piontek, M Paczkowska… - Chemistry Central …, 2013 - Springer
Background B-Lactam antibiotics are still the most common group of chemotherapeutic
drugs that are used in the treatment of bacterial infections. However, due to their chemical …

Ensuring sufficient trough plasma concentrations for broad-spectrum beta-lactam antibiotics in children with malignancies: beware of augmented renal clearance!

P André, L Diezi, K Dao, PA Crisinel… - Frontiers in …, 2022 - frontiersin.org
Introduction: Broad-spectrum beta-lactams are commonly prescribed for empirical or
selective treatment of bacterial infections in children with malignancies. In the …

Poly (bromocresol green) flakes-decorated pencil graphite electrode for selective electrochemical sensing applications and pharmacokinetic studies

MI Gadallah, HRH Ali, HF Askal, GA Saleh - Materials Science and …, 2019 - Elsevier
A square wave voltammetric method for selective determination of meropenem (MRP) and
ertapenem (ERP) was developed using pencil graphite electrode modified with poly …

Comparative Investigation into the Roles of Imipenem: Cyclodextrin Complexation and Antibiotic Combination in Combatting Antimicrobial Resistance in Gram …

SM Farhan, RMA El-Baky, HR Ahmed, Z Fathalla… - Pharmaceuticals, 2023 - mdpi.com
Extensively drug-resistant (XDR), multidrug-resistant (MDR) and pandrug-resistant (PDR)
Gram-negative microorganisms (GNBs) are considered a significant global threat. β-lactam …

Prediction of HPLC retention times of tebipenem pivoxyl and its degradation products in solid state by applying adaptive artificial neural network with recursive …

M Mizera, A Talaczyńska, P Zalewski, R Skibiński… - Talanta, 2015 - Elsevier
A sensitive and fast HPLC method using ultraviolet diode-array detector (DAD)/electrospray
ionization tandem mass spectrometry (Q-TOF-MS/MS) was developed for the determination …

Comparative review of analytical techniques for determination of carbapenems

J Cielecka-Piontek, K Michalska… - Current Analytical …, 2012 - ingentaconnect.com
The carbapenems are a group of β-lactam antibiotics. The analogs of carbapenem
(imipenem, panipenem, meropenem, ertapenem, biapenem and doripenem) used in …

A critical review of analytical methods for determination of ertapenem sodium

TM Pedroso, HRN Salgado - Critical Reviews in Analytical …, 2016 - Taylor & Francis
Antimicrobials have unquestionable importance in the control of many diseases; however
the constant concern with evolution of resistant microorganisms is increasing. Ertapenem …