Radioactive transition metals for imaging and therapy

E Boros, AB Packard - Chemical reviews, 2018 - ACS Publications
Nuclear medicine is composed of two complementary areas, imaging and therapy. Positron
emission tomography (PET) and single-photon imaging, including single-photon emission …

[HTML][HTML] Radiometals in imaging and therapy: highlighting two decades of research

S Sharma, MK Pandey - Pharmaceuticals, 2023 - mdpi.com
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

Production of radiometals in liquid targets

SJC do Carmo, PJH Scott, F Alves - EJNMMI Radiopharmacy and …, 2020 - Springer
Over the last several years, the use of radiometals has gained increasing relevance in
supporting the continuous development of new, complementary and more specific biological …

Cyclotron production of PET radiometals in liquid targets: aspects and prospects

MK Pandey, TR DeGrado - Current radiopharmaceuticals, 2021 - benthamdirect.com
The present review describes the methodological aspects and prospects of the production of
Positron Emission Tomography (PET) radiometals in a liquid target using low-medium …

Insights into trace metal metabolism in health and disease from PET:“PET metallomics”

JJ Bartnicka, PJ Blower - Journal of Nuclear Medicine, 2018 - jnm.snmjournals.org
Essential trace metals such as copper, zinc, iron, and manganese perform critical functions
in cellular and physiologic processes including catalytic, regulatory, and signaling roles …

Production of Y-86 and other radiometals for research purposes using a solution target system

E Oehlke, C Hoehr, X Hou, V Hanemaayer… - Nuclear medicine and …, 2015 - Elsevier
Introduction Diagnostic radiometals are typically obtained from cyclotrons by irradiating solid
targets or from radioisotope generators. These methods have the advantage of high …

Expanding PET-applications in life sciences with positron-emitters beyond fluorine-18

HH Coenen, J Ermert - Nuclear medicine and biology, 2021 - Elsevier
Abstract Positron-emission-tomography (PET) has become an indispensable diagnostic tool
in modern nuclear medicine. Its outstanding molecular imaging features allow repetitive …

Assessing the biocompatibility and stability of CeO 2 nanoparticle conjugates with azacrowns for use as radiopharmaceuticals

S Khabirova, M Menshikov-Tonyan, G Aleshin… - RSC Medicinal …, 2024 - pubs.rsc.org
The application of nanoparticles is promising for the purposes of nuclear medicine due to
the possibilities of using them as vectors and transporters of radionuclides. In this study, we …

Preparation and in vivo characterization of 51MnCl2 as PET tracer of Ca2+ channel-mediated transport

SA Graves, R Hernandez, HF Valdovinos, PA Ellison… - Scientific reports, 2017 - nature.com
Manganese has long been employed as a T1-shortening agent in magnetic resonance
imaging (MRI) applications, but these techniques are limited by the biotoxicity of bulk …

Reassessment of the transport mechanism of the human zinc transporter SLC39A2

MC Franz, J Pujol-Giménez, N Montalbetti… - Biochemistry, 2018 - ACS Publications
The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc
transport that could be inhibited at pH< 7.0 and stimulated by HCO3–, suggesting a …