Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

Microtubules (MT) are elongated, tubular, cytoskeletal structures formed from polymerization
of tubulin dimers. They undergo continuous cycles of polymerization and depolymerization …

Mechanoreceptor cells develop specialized mechanosensory organelles (MOs), where force-
sensitive channels and supporting structures are organized in an orderly manner to detect …

Tubulin, a heterodimer of α-and β-tubulin, is a GTPase that assembles into microtubule (MT)
polymers whose dynamic properties are intimately coupled to nucleotide hydrolysis. In cells …

Microtubules have spatiotemporally complex posttranslational modification patterns. Tubulin
tyrosine ligase-like (TTLL) enzymes introduce the most prevalent modifications on α-tubulin …

Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule
diversity, the cellular functions of which remain largely unknown. Here we show that α …

The integration of deep learning approaches in biomedical research has been
transformative, enabling breakthroughs in various applications. Despite these strides, its …

Microtubule networks are thought to be controlled by an elaborate program of tubulin
posttranslational modifications and proteins that selectively bind to modified states. A new …

An important post-translational modification (PTM) of α-tubulin is the removal of amino acids
from its C-terminus. Removal of the C-terminal tyrosine residue yields detyrosinated α …

The applicability of a deep learning model for the virtual staining of plant cell structures
using bright-field microscopy was investigated. The training dataset consisted of microscopy …