Multiple endocrine neoplasia (MEN) refers to a group of autosomal dominant disorders with
generally high penetrance that lead to the development of a wide spectrum of endocrine and …

Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

Mice lacking p27 Kip1 have been created by gene targeting in embryonic stem cells. These
mice are larger than the control animals, with thymus, pituitary, and adrenal glands and …

MENX is a recessive multiple endocrine neoplasia-like syndrome in the rat. The tumor
spectrum in MENX overlaps those of human multiple endocrine neoplasia (MEN) types 1 …

p27kip1 (p27) is a member of the universal cyclin-dependent kinase inhibitor (CDKI) family.
p27 expression is regulated by cell contact inhibition and by specific growth factors, such as …

Abstract p27Kip is a candidate human tumour-suppressor protein, because it is able to
inhibit cyclin-dependent kinases and block cell proliferation,,,,. Abnormally low levels of the …

Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been
reported in Gambian children with and without putative Ca-deficiency rickets. The aims of …

Richter's transformation denotes the development of high‐grade non‐Hodgkin lymphoma,
prolymphocytic leukemia, Hodgkin disease, or acute leukemia in patients with chronic …

Disruption of the physiologic balance between cell proliferation and death is a universal
feature of all cancers. In general terms, human B-cell lymphomas can be subdivided into 2 …

Now in its Fourth Edition, this comprehensive, practical, and thoroughly illustrated reference
offers valuable guidance in the diagnostic interpretation of lymph node biopsies. It provides …