Molecular mechanisms, characterization methods, and utilities of nanoparticle biotransformation in nanosafety assessments

X Cai, X Liu, J Jiang, M Gao, W Wang, H Zheng, S Xu… - Small, 2020 - Wiley Online Library
It is a big challenge to reveal the intrinsic cause of a nanotoxic effect due to diverse
branches of signaling pathways induced by engineered nanomaterials (ENMs) …

Harmful effects of metal (loid) oxide nanoparticles

EV Soares, HMVM Soares - Applied Microbiology and Biotechnology, 2021 - Springer
The incorporation of nanomaterials (NMs), including metal (loid) oxide (MOx) nanoparticles
(NPs), in the most diversified consumer products, has grown enormously in recent decades …

pH-responsive composite nanomaterial engineered from silica nanoparticles and luminescent mitochondrion-targeted Pt (II) complex as anticancer agent

BA Faizullin, AR Khazieva, KV Kholin… - Journal of Molecular …, 2024 - Elsevier
The present work introduces a pH-dependent adsorption of water-soluble Pt (II) complex
with diimine and alkynylphosphonium ligands ([Pt] 2+) onto a surface of silica nanoparticles …

Toxic effects of nickel oxide (NiO) nanoparticles on the freshwater alga Pseudokirchneriella subcapitata

CA Sousa, HMVM Soares, EV Soares - Aquatic Toxicology, 2018 - Elsevier
Over the last decade, concerns have been raised regarding the potential health and
environmental effects associated with the release of metal oxide nanoparticles (NPs) into …

Repeated oral dose toxicity study of nickel oxide nanoparticles in Wistar rats: a histological and biochemical perspective

N Dumala, B Mangalampalli… - Journal of Applied …, 2019 - Wiley Online Library
Despite the increasing use of nickel oxide (NiO) nanoparticles (NPs), limited information is
available on their toxicological effects. Health consequences of 28 days repeated oral …

Assessing the effect of SiO2 and TiO2 nanoparticles on granule stability and microbial community shift in aerobic granular sludge process

Y Jiang, Y Shang, W Zhang, X Zhang, J Li, S Shao - Chemosphere, 2022 - Elsevier
The widely used SiO 2 and TiO 2 nanoparticles (NPs) can accumulate in industrial
wastewaters, thereby posing challenge to biological wastewater treatment processes. In this …

Nickel oxide (NiO) nanoparticles induce loss of cell viability in yeast mediated by oxidative stress

CA Sousa, HMVM Soares… - Chemical Research in …, 2018 - ACS Publications
The present work aimed to elucidate whether the toxic effects of nickel oxide (NiO)
nanoparticles (NPs) on the yeast Saccharomyces cerevisiae were associated with oxidative …

[HTML][HTML] Whole-transcriptome sequencing revealed differentially expressed mRNAs and non-coding RNAs played crucial roles in NiONPs-induced liver fibrosis

K Li, J Zheng, H Liu, Q Gao, M Yang, J Tang… - Ecotoxicology and …, 2022 - Elsevier
Nickel oxide nanoparticles (NiONPs) induced liver fibrosis, while its mechanisms associated
with transcriptome remained unclear. This study aimed to investigate the roles of …

Toxicity of nanoparticulate nickel to aquatic organisms: review and recommendations for improvement of toxicity tests

JS Meyer, T Lyons‐Darden, ER Garman… - Environmental …, 2020 - academic.oup.com
We reviewed the literature on toxicity of nanoparticulate nickel (nano‐Ni) to aquatic
organisms, from the perspective of relevance and reliability in a regulatory framework. Our …

The effects of nickel oxide nanoparticles on structural changes, heme degradation, aggregation of hemoglobin and expression of apoptotic genes in lymphocytes

NA Gamasaee, HA Muhammad… - Journal of …, 2020 - Taylor & Francis
Abstract Nickel oxide nanoparticles (NiO NPs) have received great interests in medical and
biotechnological applications. However, their adverse impacts against biological systems …