Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines

Q Fernandes, VP Inchakalody, M Merhi… - Annals of …, 2022‏ - Taylor & Francis
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

S Galmiche, LBL Nguyen, E Tartour… - Clinical Microbiology …, 2022‏ - Elsevier
Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

Vaccination in patients with kidney failure: lessons from COVID-19

N Babel, C Hugo, TH Westhoff - Nature Reviews Nephrology, 2022‏ - nature.com
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …

Comparison of SARS-CoV-2 antibody response 4 weeks after homologous vs heterologous third vaccine dose in kidney transplant recipients: a randomized clinical …

R Reindl-Schwaighofer, A Heinzel… - JAMA internal …, 2022‏ - jamanetwork.com
Importance Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies
against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data …

A third dose of SARS‐CoV‐2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients

AH Karaba, X Zhu, T Liang, KH Wang… - American Journal of …, 2022‏ - Wiley Online Library
Abstract Vaccine‐induced SARS‐CoV‐2 antibody responses are attenuated in solid organ
transplant recipients (SOTRs) and breakthrough infections are more common. Additional …

Impact of COVID-19 on the liver and on the care of patients with chronic liver disease, hepatobiliary cancer, and liver transplantation: An updated EASL position paper

T Marjot, CS Eberhardt, T Boettler, LS Belli… - Journal of …, 2022‏ - Elsevier
The COVID-19 pandemic has presented a serious challenge to the hepatology community,
particularly healthcare professionals and patients. While the rapid development of safe and …

Application of a data-driven XGBoost model for the prediction of COVID-19 in the USA: a time-series study

Z Fang, S Yang, C Lv, S An, W Wu - BMJ open, 2022‏ - bmjopen.bmj.com
Objective The COVID-19 outbreak was first reported in Wuhan, China, and has been
acknowledged as a pandemic due to its rapid spread worldwide. Predicting the trend of …

Comparative vaccine effectiveness against severe COVID-19 over time in US hospital administrative data: a case-control study

BJ Wright, S Tideman, GA Diaz, T French… - The Lancet …, 2022‏ - thelancet.com
Background Research suggests the protection offered by COVID-19 vaccines might wane
over time, prompting consideration of booster vaccinations. Data on which vaccines offer the …

COVID-19 vaccine effectiveness among immunocompromised populations: a targeted literature review of real-world studies

M Di Fusco, J Lin, S Vaghela… - Expert Review of …, 2022‏ - Taylor & Francis
ABSTRACT Introduction From July through October of 2021, several countries issued
recommendations for increased COVID-19 vaccine protection for individuals with one or …

Heart transplantation: focus on donor recovery strategies, left ventricular assist devices, and novel therapies

MG Crespo-Leiro, MR Costanzo… - European heart …, 2022‏ - academic.oup.com
Heart transplantation is advocated in selected patients with advanced heart failure in the
absence of contraindications. Principal challenges in heart transplantation centre around an …