The overview of porous, bioactive scaffolds as instructive biomaterials for tissue regeneration and their clinical translation
Porous scaffolds have been employed for decades in the biomedical field where
researchers have been seeking to produce an environment which could approach one of …
researchers have been seeking to produce an environment which could approach one of …
[HTML][HTML] An update of nanotopographical surfaces in modulating stem cell fate: a narrative review
S Cao, Q Yuan - Biomaterials Translational, 2022 - ncbi.nlm.nih.gov
Stem cells have been one of the ideal sources for tissue regeneration owing to their
capability of self-renewal and differentiation. In vivo, the extracellular microenvironment …
capability of self-renewal and differentiation. In vivo, the extracellular microenvironment …
Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells
Long-term reconstituting haematopoietic stem cells (LT-HSCs) are used to treat blood
disorders via stem cell transplantation. The very low abundance of LT-HSCs and their rapid …
disorders via stem cell transplantation. The very low abundance of LT-HSCs and their rapid …
[HTML][HTML] Building bones for blood and beyond: the growing field of bone marrow niche model development
The bone marrow (BM) niche is a complex microenvironment that provides the signals
required for regulation of hematopoietic stem cells (HSCs) and the process of …
required for regulation of hematopoietic stem cells (HSCs) and the process of …
Extracellular vesicle cargo metabolome changes in response to the mesenchymal stromal cell microenvironment and influences cell quiescence and activation in a …
Breast cancer is the leading cause of cancer mortality in women worldwide and commonly
metastasizes to the bone marrow, drastically reducing patient prognosis and survival. In the …
metastasizes to the bone marrow, drastically reducing patient prognosis and survival. In the …
Nanotopography controls single-molecule mobility to determine overall cell fate
The addition of nanoscale distortion to ordered nanotopographies consistently determines
an osteogenic fate in stem cells. Although disordered and ordered nanopit arrays have …
an osteogenic fate in stem cells. Although disordered and ordered nanopit arrays have …
Nanoscale control by materials of mesenchymal stem cells for identification of bioactive metabolites.
MJ Dalby - ciceco.ua.pt
Metabolites, or biological small molecules, are usually considered in identification of
biomarkers. However, they can be used to drive cellular processes, such as stem cell …
biomarkers. However, they can be used to drive cellular processes, such as stem cell …