Myasthenia gravis: epidemiology, pathophysiology and clinical manifestations

L Dresser, R Wlodarski, K Rezania… - Journal of clinical medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neurological disorder characterized by defective
transmission at the neuromuscular junction. The incidence of the disease is 4.1 to 30 cases …

Drugs that induce or cause deterioration of myasthenia gravis: an update

S Sheikh, U Alvi, B Soliven, K Rezania - Journal of Clinical Medicine, 2021 - mdpi.com
Myasthenia gravis (MG) is an autoimmune neuromuscular disorder which is characterized
by presence of antibodies against acetylcholine receptors (AChRs) or other proteins of the …

Roles of GM-CSF in the pathogenesis of autoimmune diseases: an update

N Lotfi, R Thome, N Rezaei, GX Zhang… - Frontiers in …, 2019 - frontiersin.org
Granulocyte-macrophage colony-stimulating factor (GM-CSF) was first described as a
growth factor that induces the differentiation and proliferation of myeloid progenitors in the …

Roles of cytokines and T cells in the pathogenesis of myasthenia gravis

A Uzawa, S Kuwabara, S Suzuki, T Imai… - Clinical & …, 2021 - academic.oup.com
Myasthenia gravis (MG) is characterized by muscle weakness and fatigue caused by the
presence of autoantibodies against the acetylcholine receptor (AChR) or the muscle-specific …

Myasthenia gravis: pathogenic effects of autoantibodies on neuromuscular architecture

I Koneczny, R Herbst - Cells, 2019 - mdpi.com
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction (NMJ).
Autoantibodies target key molecules at the NMJ, such as the nicotinic acetylcholine receptor …

B cells in the pathophysiology of myasthenia gravis

JS Yi, JT Guptill, P Stathopoulos, RJ Nowak… - Muscle & …, 2018 - Wiley Online Library
Myasthenia gravis (MG) is an archetypal autoimmune disease. The pathology is
characterized by autoantibodies to the acetylcholine receptor (AChR) in most patients or to …

[HTML][HTML] Evolution of anti-B cell therapeutics in autoimmune neurological diseases

P Stathopoulos, MC Dalakas - Neurotherapeutics, 2022 - Elsevier
B cells have an ever-increasing role in the etiopathology of a number of autoimmune
neurological disorders, acting as antigen-presenting cells facilitating antibody production but …

Antigen-specific T cells and autoimmunity

M Rojas, Y Acosta-Ampudia, LS Heuer, W Zang… - Journal of …, 2024 - Elsevier
Autoimmune diseases (ADs) showcase the intricate balance between the immune system's
protective functions and its potential for self-inflicted damage. These disorders arise from the …

The potential for treg-enhancing therapies in nervous system pathologies

KE Olson, RL Mosley… - Clinical and Experimental …, 2023 - academic.oup.com
While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system …

Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature

F Ingelfinger, S Krishnarajah, M Kramer, SG Utz… - Acta …, 2021 - Springer
Myasthenia gravis (MG) is an autoimmune disease characterized by impaired
neuromuscular signaling due to autoantibodies targeting the acetylcholine receptor …