Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

J **e, Z Shen, Y Anraku, K Kataoka, X Chen - Biomaterials, 2019 - Elsevier
Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to …

Synthesis, bioactive properties, and biomedical applications of intrinsically therapeutic nanoparticles for disease treatment

DD Nguyen, JY Lai - Chemical Engineering Journal, 2022 - Elsevier
Intrinsically therapeutic nanoparticles (ITNPs) are a special class of nanomaterials with
capabilities of self-triggering bioactive activities (without drug) when interacting with …

[HTML][HTML] Technology and dementia: The future is now

AJ Astell, N Bouranis, J Hoey, A Lindauer… - Dementia and geriatric …, 2019 - karger.com
Background: Technology has multiple potential applications to dementia from diagnosis and
assessment to care delivery and supporting ageing in place. Objectives: To summarise key …

Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases

SM Asil, J Ahlawat, GG Barroso, M Narayan - Biomaterials science, 2020 - pubs.rsc.org
With an aging population that has been increasing in recent years, the need for the
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …

Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in polymer science, 2024 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

Preclinical development of drug delivery systems for paclitaxel-based cancer chemotherapy

F Wang, M Porter, A Konstantopoulos, P Zhang… - Journal of Controlled …, 2017 - Elsevier
Paclitaxel (PTX) is one of the most successful drugs ever used in cancer chemotherapy,
acting against a variety of cancer types. Formulating PTX with Cremophor EL and ethanol …

Codelivery of paclitaxel and temozolomide through a photopolymerizable hydrogel prevents glioblastoma recurrence after surgical resection

M Zhao, E Bozzato, N Joudiou, S Ghiassinejad… - Journal of controlled …, 2019 - Elsevier
A photopolymerizable hydrogel-based local drug delivery system was developed for the
postsurgical treatment of glioblastoma (GBM). We aimed for a local drug combination …

Advances in drug delivery technology for the treatment of glioblastoma multiforme

GD Cha, T Kang, S Baik, D Kim, SH Choi… - Journal of Controlled …, 2020 - Elsevier
Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Inhalable nanotherapeutics to improve treatment efficacy for common lung diseases

CF Anderson, ME Grimmett… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Respiratory illnesses are prevalent around the world, and inhalation‐based therapies
provide an attractive, noninvasive means of directly delivering therapeutic agents to their site …