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The emerging role of Raman spectroscopy as an omics approach for metabolic profiling and biomarker detection toward precision medicine
Omics technologies have rapidly evolved with the unprecedented potential to shape
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
precision medicine. Novel omics approaches are imperative toallow rapid and accurate data …
Informing immunotherapy with multi-omics driven machine learning
Progress in sequencing technologies and clinical experiments has revolutionized
immunotherapy on solid and hematologic malignancies. However, the benefits of …
immunotherapy on solid and hematologic malignancies. However, the benefits of …
From genotype to phenotype: Raman spectroscopy and machine learning for label-free single-cell analysis
Y Zhang, K Chang, B Ogunlade, L Herndon… - ACS …, 2024 - ACS Publications
Raman spectroscopy has made significant progress in biosensing and clinical research.
Here, we describe how surface-enhanced Raman spectroscopy (SERS) assisted with …
Here, we describe how surface-enhanced Raman spectroscopy (SERS) assisted with …
Novel aspects of Raman spectroscopy in skin research
The analytical technology of Raman spectroscopy has an almost 100‐year history. During
this period, many modifications and developments happened in the method like discovery of …
this period, many modifications and developments happened in the method like discovery of …
Absolute quantification of serum exosomes in patients with an sers-lateral flow strip biosensor for noninvasive clinical cancer diagnosis
Exosomes (exos) widely existing in body fluids show great potential for noninvasive cancer
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …
diagnosis. Quantitative analysis of exos is traditionally performed by targeting specific …
Metabolic response to small molecule therapy in colorectal cancer tracked with Raman spectroscopy and metabolomics
Despite numerous screening tools for colorectal cancer (CRC), 25% of patients are
diagnosed with advanced disease. Novel diagnostic technologies that are early, accurate …
diagnosed with advanced disease. Novel diagnostic technologies that are early, accurate …
Label-free plasmon-enhanced spectroscopic HER2 detection for dynamic therapeutic surveillance of breast cancer
The expression of human epidermal growth factor receptor-2 (HER2) has important
implications for pathogenesis, progression, and therapeutic efficacy of breast cancer. The …
implications for pathogenesis, progression, and therapeutic efficacy of breast cancer. The …
Optical diffraction tomography and Raman spectroscopy reveal distinct cellular phenotypes during white and brown adipocyte differentiation
White adipose tissue (WAT) and brown adipose tissue (BAT) are the primary types of fats in
humans, and they play prominent roles in energy storage and thermogenesis, respectively …
humans, and they play prominent roles in energy storage and thermogenesis, respectively …
Rapid, label-free classification of glioblastoma differentiation status combining confocal Raman spectroscopy and machine learning
LM Wurm, B Fischer, V Neuschmelting, D Reinecke… - Analyst, 2023 - pubs.rsc.org
Label-free identification of tumor cells using spectroscopic assays has emerged as a
technological innovation with a proven ability for rapid implementation in clinical care …
technological innovation with a proven ability for rapid implementation in clinical care …
Raman spectroscopy combined with a support vector machine algorithm as a diagnostic technique for primary Sjögren's syndrome
X Chen, X Wu, C Chen, C Luo, Y Shi, Z Li, X Lv… - Scientific Reports, 2023 - nature.com
The aim of this study was to explore the feasibility of Raman spectroscopy combined with
computer algorithms in the diagnosis of primary Sjögren syndrome (pSS). In this study …
computer algorithms in the diagnosis of primary Sjögren syndrome (pSS). In this study …